Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
7476 results
Cited 2 times since 2023 (6.1 per year) source: EuropePMC
European heart journal. Quality of care & clinical outcomes, Volume 9, Issue 8, 1 1 2023, Pages 778-784 The impact of atrial fibrillation on prognosis in aortic stenosis. Laenens D, Stassen J, Galloo X, Ewe SH, Singh GK, Ammanullah MR, Hirasawa K, Sia CH, Butcher SC, Chew NWS, Kong WKF, Poh KK, Ding ZP, Ajmone Marsan N, Bax JJ
Background: Atrial fibrillation (AF) and aortic stenosis (AS) are both highly prevalent and often coexist. Various studies have focused on the prognostic value of AF in patients with AS, but rarely considered left ventricular (LV) diastolic function as a prognostic factor. Objective: To evaluate the prognostic impact of AF in patients with AS while correcting for LV diastolic function. Methods: Patients with first diagnosis of significant AS were selected and stratified according to history of A... Abstract
JACC. Clinical electrophysiology, Volume 9, Issue 12, 1 1 2023, Pages 2662-2663 Reply: Association of Adverse Events With the Different Diagnostic Schemes of Cardiac Sarcoidosis. Myadam R, Crawford TC, Bogun FM, Gu X, Ellenbogen KA, Jasti S, Chicos AB, Roukoz H, Zimetbaum PJ, Kalbfleisch SJ, Murgatroyd FD, Steckman DA, Rosenfeld LE, Garlitski AC, Soejima K, Bhan AK, Vedantham V, Dickfeld TL, De Lurgio DB, Platonov PG, Zipse MM, Nishiuchi S, Ortman ML, Narasimhan C, Patton KK, Rosenthal DG, Mukerji SS, Hoogendoorn JC, Zeppenfeld K, Sauer WH, Kron J, Cardiac Sarcoidosis Consortium
JACC. Clinical electrophysiology, 1 1 2023, Pages S2405-500X(23)00816-2 Mapping and Ablation of Ventricular Tachycardia in Inherited Left Ventricular Cardiomyopathies. Zeppenfeld K, Kimura Y, Ebert M
Advances in the field of human genetics have led to an accumulating understanding of the genetic basis of distinct nonischemic cardiomyopathies associated with ventricular tachycardias (VTs) and sudden cardiac death. To date, there is an increasing proportion of patients with inherited cardiomyopathies requiring catheter ablation for VTs. This review provides an overview of disease-causing gene mutations frequently encountered and relevant for clinical electrophysiologists. Available data on VT... Abstract
Giornale italiano di cardiologia (2006), Volume 24, Issue 12 Suppl 1, 1 1 2023, Pages e1-e101 [2023 ESC Guidelines for the management of endocarditis]. Marsan NA, de Waha S, Bonaros N, Brida M, Burri H, Caselli S, Doenst T, Ederhy S, Erba PA, Foldager D, Fosbø EL, Kovac J, Mestres CA, Miller OI, Miro JM, Pazdernik M, Pizzi MN, Quintana E, Rasmussen TB, Ristić AD, Rodés-Cabau J, Sionis A, Zühlke LJ, ESC Scientific Document Group, Delgado V, Borger MA
Molecular oncology, 27 4 2023 Identification of protein biomarkers for prediction of response to platinum-based treatment regimens in patients with non-small cell lung cancer. Böttger F, Radonic T, Bahce I, Monkhorst K, Piersma SR, Pham TV, Dingemans AC, Hillen LM, Santarpia M, Giovannetti E, Smit EF, Burgers SA, Jimenez CR
The majority of patients with resected stage II-IIIA non-small cell lung cancer (NSCLC) are treated with platinum-based adjuvant chemotherapy (ACT) in a one-size-fits-all approach. However, a significant number of patients do not derive clinical benefit, and no predictive patient selection biomarker is currently available. Using mass spectrometry-based proteomics, we have profiled tumour resection material of 2 independent, multi-centre cohorts of in total 67 patients with NSCLC who underwent AC... Abstract
Cited 1 times since 2023 (2.9 per year) source: EuropePMC
Cancer treatment reviews, Volume 122, 25 4 2023, Pages 102664 The role of anti-EGFR therapies in EGFR-TKI-resistant advanced non-small cell lung cancer. Ciardiello F, Hirsch FR, Pirker R, Felip E, Valencia C, Smit EF
Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are the current recommended option for the first-line treatment of patients with EGFR-mutant non-small cell lung cancer (NSCLC). Resistance to first-generation TKIs led to the development of second- and third-generation TKIs with improved clinical outcomes. However, sequential administration of TKIs has led to the emergence of new EGFR resistance mutations and persistent tumor cell survival. This evidence highlights the pote... Abstract
The Journal of investigative dermatology, 25 4 2023, Pages S0022-202X(23)03115-9 Characterization of Patient-Derived GNAQ Mutated Endothelial Cells from Capillary Malformations. Langbroek GB, Stor MLE, Janssen V, de Haan A, Horbach SER, Graupera M, van Noesel CJM, van der Horst CMAM, Wolkerstorfer A, Huveneers S
Capillary malformations (CM) (port-wine stains) are congenital skin lesions that are characterized by dilated capillaries and postcapillary venules. CMs are caused by altered functioning of the vascular endothelium. Somatic genetic mutations have predominantly been identified in the endothelial cells of CMs, providing an opportunity for the development of targeted therapies. However, there is currently limited in-depth mechanistic insight into the pathophysiology and a lack of preclinical resear... Abstract
Cited 1 times since 2023 (2.8 per year) source: EuropePMC
Soft matter, Volume 19, Issue 45, 22 4 2023, Pages 8832-8848 Hydrophobically modified complex coacervates for designing aqueous pressure-sensitive adhesives. van Westerveld L, Es Sayed J, de Graaf M, Hofman AH, Kamperman M, Parisi D
The rheology of complex coacervates can be elegantly tuned via the design and control of specific non-covalent hydrophobic interactions between the complexed polymer chains. The well-controlled balance between elasticity and energy dissipation makes complex coacervates perfect candidates for pressure-sensitive adhesives (PSAs). In this work, the polyanion poly(3-sulfopropyl methacrylate) (PSPMA) and the polycation quaternized poly(4-vinylpyridine) (QP4VP) were used to prepare complex coacervates... Abstract
The Journal of cardiovascular surgery, 21 3 2023 The association between sarcopenia and adverse outcomes after complex endovascular aortic repair. Warmerdam BW, van Rijswijk CS, Droop A, Lucassen CJ, Hamming JF, van Schaik J, van der Vorst JR
Background: Sarcopenia is identified as a predictive factor for adverse outcomes after complex endovascular aortic repair (complex EVAR). Consensus on preferred parameters for sarcopenia is not yet reached. The current study compares three CT-assessed parameters on their association with adverse outcomes after complex EVAR. Methods: This was a single-center retrospective cohort study. Psoas Muscle Index (PMI), Skeletal Muscle Index (SMI), and lean psoas muscle area (LPMA) were examined by CT-seg... Abstract
Cited 2 times since 2023 (5.5 per year) source: EuropePMC
Biosensors & bioelectronics, Volume 245, 17 3 2023, Pages 115836 SERS-based pH-Dependent detection of sulfites in wine by hydrogel nanocomposites. Yilmaz D, Miranda B, Lonardo E, Rea I, De Stefano L, De Luca AC
Sulfur dioxide (SO2) and sulfites are well-known additives in winemaking due to their preservative properties. Although they can prevent oxidation and inhibit microbial growth, they pose health risks and require limitations on their use. Consequently, the total level of SO2 is regulated and several quantification strategies have been proposed. The approved detection methods require the extraction of SO2 by heating and/or acid treatment. Then, iodine or acid/base titrations are conducted for the... Abstract
European journal of heart failure, Volume 26, Issue 1, 16 3 2023, Pages 117-126 Short-term effects of sacubitril/valsartan therapy on myocardial oxygen consumption and energetic efficiency of cardiac work in heart failure with reduced ejection fraction: A randomized controlled study. Nesterov SV, Räty J, Nammas W, Maaniitty T, Galloo X, Stassen J, Laurila S, Vasankari T, Huusko J, Bax JJ, Saraste A, Knuuti J
Aims: We sought to evaluate the mechanism of angiotensin receptor-neprilysin inhibitor (ARNI) sacubitril/valsartan therapy and compare it with a valsartan-only control group in patients with heart failure with reduced ejection fraction (HFrEF). Methods and results: The study was a phase IV, prospective, randomized, double-blind, parallel-group study in patients with New York Heart Association class II-III heart failure and left ventricular ejection fraction (LVEF) ≤35%. During a 6-week run-in pe... Abstract
Vascular, 11 2 2023, Pages 17085381231214324 High on-treatment platelet reactivity in peripheral arterial disease: A systematic review. Goncalves LN, van Velze V, Klok FA, Gal P, Vos RC, Hamming JF, van der Bogt KEA
Objectives: To highlight current evidence pertaining to the measurement methods and prevalence of high on-treatment platelet reactivity (HTPR) in patients with PAD, as well as to evaluate the relationship between HTPR and recurrent adverse cardiovascular and limb events in PAD patients. Methods: A systematic review of English-language literature on HTPR in patients with PAD. An electronic literature search of PubMed and Medline was performed in May 2021. Results: A total of 29 studies with a tot... Abstract
Journal of cardiovascular computed tomography, Volume 18, Issue 1, 10 2 2023, Pages 11-17 Rationale and design of the CONFIRM2 (Quantitative COroNary CT Angiography Evaluation For Evaluation of Clinical Outcomes: An InteRnational, Multicenter Registry) study. van Rosendael AR, Crabtree T, Bax JJ, Nakanishi R, Mushtaq S, Pontone G, Andreini D, Buechel RR, Gräni C, Feuchtner G, Patel TR, Choi AD, Al-Mallah M, Nabi F, Karlsberg RP, Rochitte CE, Alasnag M, Hamdan A, Cademartiri F, Marques H, Kalra D, German DM, Gupta H, Hadamitzky M, Deaño RC, Khalique O, Knaapen P, Hoffmann U, Earls J, Min JK, Danad I, CONFIRM 2 investigators
Background: In the last 15 years, large registries and several randomized clinical trials have demonstrated the diagnostic and prognostic value of coronary computed tomography angiography (CCTA). Advances in CT scanner technology and developments of analytic tools now enable accurate quantification of coronary artery disease (CAD), including total coronary plaque volume and low attenuation plaque volume. The primary aim of CONFIRM2, (Quantitative COroNary CT Angiography Evaluation For Evaluation... Abstract
Cited 1 times since 2023 (2.6 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 32, Issue 1, 9 2 2023, Pages 38-44 Brief lifestyle advice in cardiac care: an experimental study on message source and framing. IJzerman RVH, van der Vaart R, Breeman LD, van den Broek I, Keesman M, Kraaijenhagen RA, Reijnders T, Weerts M, Evers AWM, Scholte Op Reimer WJM, Janssen VR, BENEFIT consortium
Objective: Communicating risk information and offering lifestyle advice are important goals in cardiac rehabilitation. However, the most effective way and the most effective source to communicate this information are not yet known. Therefore, we examined the effect of source (cardiologist, physiotherapist) and framing (gain, loss) of brief lifestyle advice on patients' intention-to-change-lifestyle. Methods: In an online experimental study, 636 cardiac patients (40% female, 67 (10) yrs.) we... Abstract
Pediatric pulmonology, Volume 59, Issue 2, 8 2 2023, Pages 263-273 The effects of the COVID-19 pandemic on PICU admissions for severe asthma exacerbations: A single-center experience. Bazdar S, van den Berg S, Rutjes NW, Bloemsma LD, Downward GS, De Weger LA, Terheggen-Lagro SWJ, van Wijck Y, Maitland van der Zee AH, Kapitein B
Background: The incidence of severe asthma exacerbations (SAE) requiring a pediatric intensive care unit (PICU) admission during the coronavirus disease 2019 (COVID-19) pandemic (and its association with public restrictions) is largely unknown. We examined the trend of SAE requiring PICU admission before, during, and after COVID-19 restrictions in Amsterdam, the Netherlands, and its relationship with features such as environmental triggers and changes in COVID-19 restriction measures. Methods: I... Abstract
Cited 3 times since 2023 (7.7 per year) source: EuropePMC
Cell reports. Medicine, Volume 4, Issue 11, 8 2 2023, Pages 101280 Tepotinib in patients with non-small cell lung cancer with high-level MET amplification detected by liquid biopsy: VISION Cohort B. Le X, Paz-Ares LG, Van Meerbeeck J, Viteri S, Galvez CC, Smit EF, Garassino M, Veillon R, Baz DV, Pradera JF, Sereno M, Kozuki T, Kim YC, Yoo SS, Han JY, Kang JH, Son CH, Choi YJ, Stroh C, Juraeva D, Vioix H, Bruns R, Otto G, Johne A, Paik PK
High-level MET amplification (METamp) is a primary driver in ∼1%-2% of non-small cell lung cancers (NSCLCs). Cohort B of the phase 2 VISION trial evaluates tepotinib, an oral MET inhibitor, in patients with advanced NSCLC with high-level METamp who were enrolled by liquid biopsy. While the study was halted before the enrollment of the planned 60 patients, the results of 24 enrolled patients are presented here. The objective response rate (ORR) is 41.7% (95% confidence interval [CI], 22.1-63.4),... Abstract
Microorganisms, Volume 11, Issue 11, 3 1 2023, Pages 2698 Unusual Oligomeric Laccase-like Oxidases from Ascomycete <i>Curvularia geniculata</i> VKM F-3561 Polymerizing Phenylpropanoids and Phenolic Compounds under Neutral Environmental Conditions. Renfeld ZV, Chernykh AM, Baskunov BP, Gaidina AS, Myasoedova NM, Egorova AD, Moiseeva OV, Gorina SY, Kolomytseva MP
The unique oligomeric alkaliphilic laccase-like oxidases of the ascomycete C. geniculata VKM F-3561 (with molecular masses about 1035 and 870 kDa) were purified and characterized for the first time. The ability of the enzymes to oxidize phenylpropanoids and phenolic compounds under neutral environmental conditions with the formation of previously unknown di-, tri-, and tetrameric products of transformation was shown. The possibility to obtain industrially valuable compounds (dihydroxybenzyl alco... Abstract
International journal of radiation oncology, biology, physics, Volume 118, Issue 3, 3 1 2023, Pages 639-649 Predicting Radiation-Induced Lung Injury in Patients With Lung Cancer: Challenges and Opportunities. Kuipers ME, van Doorn-Wink KCJ, Hiemstra PS, Slats AM
Radiation-induced lung injury (RILI) is one of the main dose-limiting toxicities in radiation therapy (RT) for lung cancer. Approximately 10% to 20% of patients show signs of RILI of variable severity. The reason for the wide range of RILI severity and the mechanisms underlying its development are only partially understood. A number of clinical risk factors have been identified that can aid in clinical decision making. Technological advancements in RT and the use of strict organ-at-risk dose con... Abstract
JTCVS open, Volume 16, 2 1 2023, Pages 619-627 Simulation-based assessment of robotic cardiac surgery skills: An international multicenter, cross-specialty trial. Atroshchenko GV, Navarra E, Valdis M, Sandoval E, Hashemi N, Cerny S, Pereda D, Palmen M, Bjerrum F, Bruun NH, Tolsgaard MG
Objective: This study aimed to investigate the validity of simulation-based assessment of robotic-assisted cardiac surgery skills using a wet lab model, focusing on the use of a time-based score (TBS) and modified Global Evaluative Assessment of Robotic Skills (mGEARS) score. Methods: We tested 3 wet lab tasks (atrial closure, mitral annular stitches, and internal thoracic artery [ITA] dissection) with both experienced robotic cardiac surgeons and novices from multiple European centers. The task... Abstract
Cited 1 times since 2023 (2.4 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 82, Issue 20, 1 1 2023, Pages 1953-1966 Imaging Methods for Evaluation of Chronic Aortic Regurgitation in Adults: JACC State-of-the-Art Review. Ranard LS, Bonow RO, Nishimura R, Mack MJ, Thourani VH, Bavaria J, O'Gara PT, Bax JJ, Blanke P, Delgado V, Leipsic J, Lang RM, Michelena HI, Cavalcante JL, Vahl TP, Leon MB, Rigolin VH, Heart Valve Collaboratory
A global multidisciplinary workshop was convened to discuss the multimodality diagnostic evaluation of aortic regurgitation (AR). Specifically, the focus was on assessment tools for AR severity and analyzing evolving data on the optimal timing of aortic valve intervention. The key concepts from this expert panel are summarized as: 1) echocardiography is the primary imaging modality for assessment of AR severity; however, when data is incongruent or incomplete, cardiac magnetic resonance may be h... Abstract