Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
29 results
Revista espanola de cardiologia (English ed.), 24 4 2022, Pages S1885-5857(22)00160-8 Fusion imaging in congenital heart disease: just a pretty picture or a new tool to improve patient management? Regeer MV, Marsan NA
Frontiers in cardiovascular medicine, Volume 9, 10 2 2022, Pages 870459 Atrioventricular Block Necessitating Chronic Ventricular Pacing After Tricuspid Valve Surgery in Patients With a Systemic Right Ventricle: Long-Term Follow-Up. Nederend M, Jongbloed MRM, Kiès P, Vliegen HW, Bouma BJ, Regeer MV, Koolbergen DR, Hazekamp MG, Schalij MJ, Egorova AD
Background: Patients with transposition of the great arteries (TGA) after an atrial switch or congenitally corrected TGA (ccTGA) are prone to systemic right ventricular (sRV) failure. Tricuspid valve (TV) regurgitation aggravates sRV dysfunction. Timely TV surgery stabilizes sRV function, yet the development of atrioventricular (AV)-conduction disturbances in the course of sRV failure can contribute to sRV dysfunction through pacing-induced dyssynchrony. This study aims to explore the incidence,... Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 29, Issue 3, 2 1 2020, Pages 173-174 Broad complex tachycardia; never judge a book by its cover. Regeer MV, Tops LF, de Riva Silva M
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 29, Issue 3, 2 1 2020, Pages 168-171 Broad complex tachycardia; never judge a book by its cover. Regeer MV, Tops LF, de Riva Silva M
Cited 3 times since 2020 (1.4 per year) source: EuropePMC
European heart journal. Case reports, Volume 4, Issue 3, 17 3 2020, Pages 1-5 Anomalous left coronary artery from the pulmonary artery: a rare cause of an out-of-hospital cardiac arrest in an adult-a case report. Regeer MV, Bondarenko O, Zeppenfeld K, Egorova AD
Background: Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital disorder resulting in ischaemia and myocardial infarction which can act as a potential substrate for life-threatening arrhythmias and sudden cardiac death. Case summary: A 19-year-old man was admitted to the hospital after successful resuscitation from an out-of-hospital cardiac arrest (OHCA) due to ventricular fibrillation occurring during jogging. In the diagnostic work-up of the OHCA, computed t... Abstract
Cited 4 times since 2019 (1.5 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 20, Issue 10, 1 1 2019, Pages 1105-1111 Time course of left ventricular remodelling and mechanics after aortic valve surgery: aortic stenosis vs. aortic regurgitation. Vollema EM, Singh GK, Prihadi EA, Regeer MV, Ewe SH, Ng ACT, Mertens BJA, Klautz RJM, Ajmone Marsan N, Bax JJ, Delgado V
AIMS:Pressure overload in aortic stenosis (AS) and both pressure and volume overload in aortic regurgitation (AR) induce concentric and eccentric hypertrophy, respectively. These structural changes influence left ventricular (LV) mechanics, but little is known about the time course of LV remodelling and mechanics after aortic valve surgery (AVR) and its differences in AS vs. AR. The present study aimed to characterize the time course of LV mass index (LVMI) and LV mechanics [by LV global longitu... Abstract
Cited 11 times since 2018 (2.7 per year) source: EuropePMC
The American journal of cardiology, Volume 122, Issue 4, 4 1 2018, Pages 584-591 Relation of Echocardiographic Markers of Left Atrial Fibrosis to Atrial Fibrillation Burden. Leung M, Abou R, van Rosendael PJ, van der Bijl P, van Wijngaarden SE, Regeer MV, Podlesnikar T, Ajmone Marsan N, Leung DY, Delgado V, Bax JJ
In patients with atrial fibrillation (AF), left atrial (LA) fibrosis is a major determinant of the progression to, and burden of AF. LA reservoir strain and total atrial conduction time (PA-TDI) reflect LA fibrotic content. We aimed to investigate the relation between LA reservoir strain and PA-TDI in AF patients and control subjects. Six-hundred two patients (mean age 56 years, 53% men) with first episode of AF and 342 controls (mean age 64 years, 71% men) without structural heart disease under... Abstract
Cited 13 times since 2018 (3.1 per year) source: EuropePMC
European heart journal, Volume 39, Issue 15, 1 1 2018, Pages 1308-1313 Inter-ethnic differences in valve morphology, valvular dysfunction, and aortopathy between Asian and European patients with bicuspid aortic valve. Kong WKF, Regeer MV, Poh KK, Yip JW, van Rosendael PJ, Yeo TC, Tay E, Kamperidis V, van der Velde ET, Mertens B, Ajmone Marsan N, Delgado V, Bax JJ
Background: Transcatheter aortic valve replacement (TAVR) has been shown safe and feasible in patients with bicuspid aortic valve (BAV) morphology. Evaluation of inter-ethnic differences in valve morphology and function and aortic root dimensions in patients with BAV is important for the worldwide spread of this therapy in this subgroup of patients. Comparisons between large European and Asian cohorts of patients with BAV have not been performed, and potential differences between populations may... Abstract
Cited 9 times since 2018 (2 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 19, Issue 2, 1 1 2018, Pages 176-184 Three-dimensional assessment of mitral valve annulus dynamics and impact on quantification of mitral regurgitation. van Wijngaarden SE, Kamperidis V, Regeer MV, Palmen M, Schalij MJ, Klautz RJ, Bax JJ, Ajmone Marsan N, Delgado V
Aims: To assess mitral annulus dynamics in primary and secondary mitral regurgitation (MR) with 3-dimensional transesophageal echocardiography (3D TEE) and the impact on MR quantification. Methods and results: One hundred and twenty-three patients with moderate and severe MR (63 ± 11 years, 78 males) and 29 controls (59 ± 15 years, 19 males) were evaluated. Functional MR (FMR) was present in 31 patients, fibroelastic deficiency (FED) in 52 and Barlow's disease (BD) in 40. Annular geometry w... Abstract
Cited 5 times since 2018 (1.1 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 19, Issue 2, 1 1 2018, Pages 208-215 Mitral valve repair for secondary mitral regurgitation in non-ischaemic dilated cardiomyopathy is associated with left ventricular reverse remodelling and increase of forward flow. Kamperidis V, van Wijngaarden SE, van Rosendael PJ, Kong WKF, Regeer MV, van der Kley F, Sianos G, Ajmone Marsan N, Bax JJ, Delgado V
Aims: It remains unclear whether surgical or transcatheter mitral valve repair for secondary mitral regurgitation (MR) in patients with non-ischaemic cardiomyopathy reverse the underlying left ventricular (LV) pathophysiology. We hypothesized that mitral valve repair improves LV systolic function and forward flow and induces LV reverse remodelling in this group of patients. Methods and results: Seventy-six patients (65 ± 14 years old, 43% male) with non-ischaemic cardiomyopathy and moderate to s... Abstract
Cited 2 times since 2017 (0.4 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 18, Issue 9, 1 1 2017, Pages 1041-1048 Three-dimensional transoesophageal echocardiography of the aortic valve and root: changes in aortic root dilation and aortic regurgitation. Regeer MV, Kamperidis V, Versteegh MIM, Schalij MJ, Marsan NA, Bax JJ, Delgado V
Aims: It has been hypothesized that in response to dilation of the aortic root, the aortic valve cusps may remodel to prevent aortic regurgitation (AR). The aim of the present study was to evaluate the association between aortic cusp dimensions and aortic root geometry. Methods and results: Three-dimensional transoesophageal echocardiography was performed in 40 patients with aortic root dilation (mean age 57 ± 12 years, 75% men, 35% bicuspid aortic valve) and 20 controls with a normal aortic roo... Abstract
Cited 18 times since 2017 (3.4 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 10, Issue 3, 1 1 2017, Pages e005155 Sex Differences in Phenotypes of Bicuspid Aortic Valve and Aortopathy: Insights From a Large Multicenter, International Registry. Kong WK, Regeer MV, Ng AC, McCormack L, Poh KK, Yeo TC, Shanks M, Parent S, Enache R, Popescu BA, Yip JW, Ma L, Kamperidis V, van der Velde ET, Mertens B, Ajmone Marsan N, Delgado V, Bax JJ
This large multicenter, international bicuspid aortic valve (BAV) registry aimed to define the sex differences in prevalence, valve morphology, dysfunction (aortic stenosis/regurgitation), aortopathy, and complications (endocarditis and aortic dissection). Demographic, clinical, and echocardiographic data at first presentation of 1992 patients with BAV (71.5% men) were retrospectively analyzed. BAV morphology and valve function were assessed; aortopathy configuration was defined as isolated dila... Abstract
Cited 30 times since 2017 (5.6 per year) source: EuropePMC
JAMA cardiology, Volume 2, Issue 3, 1 1 2017, Pages 285-292 Prognostic Implications of Raphe in Bicuspid Aortic Valve Anatomy. Kong WK, Delgado V, Poh KK, Regeer MV, Ng AC, McCormack L, Yeo TC, Shanks M, Parent S, Enache R, Popescu BA, Liang M, Yip JW, Ma LC, Kamperidis V, van Rosendael PJ, van der Velde ET, Ajmone Marsan N, Bax JJ
Importance: Little is known about the association between bicuspid aortic valve (BAV) morphologic findings and the degree of valvular dysfunction, presence of aortopathy, and complications, including aortic valve surgery, aortic dissection, and all-cause mortality. Objective: To investigate the association between BAV morphologic findings (raphe vs nonraphe) and the degree of valve dysfunction, presence of aortopathy, and prognosis (including need for aortic valve surgery, aortic dissection, and... Abstract
Cited 5 times since 2017 (0.9 per year) source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, Volume 12, Issue 13, 1 1 2017, Pages 1660-1666 Left bundle branch block after sutureless, transcatheter, and stented biological aortic valve replacement for aortic stenosis. Regeer MV, Merkestein LR, de Weger A, Kamperidis V, van der Kley F, van Rosendael PJ, Marsan NA, Klautz RJ, Schalij MJ, Bax JJ, Delgado V
Aims: Conventional aortic valve replacement (AVR), sutureless AVR (su-AVR) and transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS) are associated with conduction abnormalities. The aim of the present study was to assess the incidence of left bundle branch block (LBBB) after su-AVR and TAVI, in comparison to conventional AVR. Methods and results: A total of 501 patients (mean age 74±8 years, 53% male) without preoperative cardiac conduction disturbances who underwent AV... Abstract
Cited 4 times since 2016 (0.7 per year) source: EuropePMC
Journal of cardiovascular computed tomography, Volume 11, Issue 1, 25 4 2016, Pages 1-7 Prognostic implications of descending thoracic aorta dilation after surgery for aortic dissection. Regeer MV, Martina B, Versteegh MI, de Weger A, Klautz RJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Background: The present study assessed whether descending thoracic aorta growth can be measured reliably by volumetric analysis using multi-detector row computed tomography (MDCT) and whether growth influences the need for future aortic interventions in survivors of acute type A aortic dissection. Methods: A total of 51 patients (58 ± 11 years, 61% male) who underwent surgery for type A aortic dissection with ≥2 postoperative MDCT scans ≥5 months apart were included. Volumetric analysis of the d... Abstract
Cited 12 times since 2016 (2 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 102, Issue 6, 22 4 2016, Pages 1981-1987 Effect of Aortic Valve Replacement on Aortic Root Dilatation Rate in Patients With Bicuspid and Tricuspid Aortic Valves. Regeer MV, Versteegh MI, Klautz RJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Background: It remains unclear whether aortic valve replacement (AVR) has an effect on the aortic root dilatation rate in patients with bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV). The present study evaluated the pre- and postoperative annual aortic root dilatation rates in BAV and TAV. Methods: A total of 93 patients (67 ± 11 years; 71% men) who underwent AVR between 2003 and 2013 and had at least 2 pre- and postoperative echocardiographic studies 1 year or more apart were incl... Abstract
Cited 8 times since 2016 (1.3 per year) source: EuropePMC
Echocardiography (Mount Kisco, N.Y.), Volume 33, Issue 10, 25 4 2016, Pages 1458-1464 Left ventricular reverse remodeling after aortic valve surgery for acute versus chronic aortic regurgitation. Regeer MV, Versteegh MI, Ajmone Marsan N, Schalij MJ, Klautz RJ, Bax JJ, Delgado V
Aims: Extent of left ventricular (LV) reverse remodeling after aortic valve repair or replacement (AVR) may differ between patients operated for acute aortic regurgitation (AR) and chronic AR. The aim of this study was to compare changes in LV volumes and function between patients with acute and chronic AR who underwent AVR. Methods and results: A total of 98 patients (54±15 years, 61% men) with acute (n=21) or chronic AR (n=77) were included in the present retrospective evaluation. LV volumes,... Abstract
Cited 3 times since 2016 (0.5 per year) source: EuropePMC
The American journal of cardiology, Volume 118, Issue 4, 29 5 2016, Pages 567-571 Impact of Different Iterations of Devices and Degree of Aortic Valve Calcium on Paravalvular Regurgitation After Transcatheter Aortic Valve Implantation. Kong WK, van Rosendael PJ, van der Kley F, de Weger A, Kamperidis V, Regeer MV, Marsan NA, Bax JJ, Delgado V
The iterations of the SAPIEN prosthesis might impact the incidence and grade of paravalvular regurgitation (PVR). The aim of this study was to assess the impact of iterations of balloon-expandable valves (SAPIEN, SAPIEN XT, and SAPIEN 3) and degree of aortic valve calcification (AVC) on the severity of PVR after transcatheter aortic valve implantation (TAVI). Comprehensive echocardiographic examinations and multidetector computed tomography (MDCT) were performed in 272 patients (127 men, 81 ± 7 ... Abstract
The American journal of cardiology, Volume 117, Issue 7, 2 1 2016, Pages 1167-1172 Comparison of Left Ventricular Volume and Ejection Fraction and Frequency and Extent of Aortic Regurgitation After Operative Repair of Type A Aortic Dissection Among Three Different Surgical Techniques. Regeer MV, Versteegh MI, Klautz RJ, Schalij MJ, Bax JJ, Marsan NA, Delgado V
Differences in recurrence rate of aortic regurgitation (AR) and extent of left ventricular (LV) remodeling across the different surgical options in patients operated for type A aortic dissection remain unknown. The present evaluation compared the AR recurrence rate and changes in LV volumes and systolic function in valve-sparing aorta replacement (VSAR), supracoronary ascending aorta replacement (SCAR), and aortic valve and aorta replacement (AVAR). A total of 97 patients (58 ± 12 years, 62% men... Abstract
Expert review of cardiovascular therapy, Volume 14, Issue 1, 4 1 2015, Pages 75-86 The role of multimodality imaging in the selection of patients for aortic valve repair. Regeer MV, Versteegh MI, Marsan NA, Bax JJ, Delgado V
Aortic valve sparing surgery for aortic regurgitation and/or aortopathy serves as an alternative to aortic valve and root replacement. One of the advantages of aortic valve sparing surgery over conventional replacement is that there is no need for life-long anticoagulation, which is particularly attractive in young patients who may receive a mechanical prosthesis otherwise. However, successful aortic valve repair requires high expertise. At present, reparability is determined intraoperatively by... Abstract