Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
196 results
Cited 49 times since 2011 (3.9 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 58, Issue 18, 6 1 2011, Pages 1910-1918 Hemodynamic and clinical impact of prosthesis-patient mismatch after transcatheter aortic valve implantation. Ewe SH, Muratori M, Delgado V, Pepi M, Tamborini G, Fusini L, Klautz RJ, Gripari P, Bax JJ, Fusari M, Schalij MJ, Marsan NA
Objectives: This study examined the mid-term hemodynamic and clinical impact of prosthesis-patient mismatch (PPM) in patients undergoing transcatheter aortic valve implantation (TAVI) with balloon-expandable valves. Background: PPM can be observed after aortic valve surgery. However, little is known about the incidence of PPM in patients undergoing TAVI. Methods: Echocardiography and clinical assessment were performed in 165 patients at baseline, before hospital discharge, and at 6 months after... Abstract
Cited 5 times since 2011 (0.4 per year) source: EuropePMC
European journal of heart failure, Volume 13, Issue 11, 16 3 2011, Pages 1202-1210 Myocardial collagen turnover after surgical ventricular restoration in heart failure patients. ten Brinke EA, Witkowski TG, Delgado V, Klein P, Klok M, Marsan NA, Klautz RJ, van der Wall EE, Bax JJ, van der Laarse A, Steendijk P
Aims: Surgical ventricular restoration (SVR) aims to normalize left ventricular (LV) volume and shape in patients with ischaemic cardiomyopathy and anterior wall scar. The chronic effects on LV function may depend on alterations in myocardial collagen metabolism. The present study evaluated myocardial collagen synthesis and degradation rates at baseline and at 6 months follow-up after SVR. We hypothesize that the chronic effects of SVR on LV function and clinical outcome depend on alterations in... Abstract
Cited 8 times since 2011 (0.6 per year) source: EuropePMC
Heart rhythm, Volume 9, Issue 1, 5 1 2011, Pages 10-17 Catheter ablation of ventricular tachycardia after left ventricular reconstructive surgery for ischemic cardiomyopathy. Wijnmaalen AP, Roberts-Thomson KC, Steven D, Klautz RJ, Willems S, Schalij MJ, Stevenson WG, Zeppenfeld K
Background: After surgical ventricular restoration (SVR) for ischemic cardiomyopathy, ventricular tachycardias (VTs) are an important reason for postoperative morbidity and mortality. Objective: The purpose of this study was to elucidate the VT substrate, VT characteristics, and outcome of radiofrequency catheter ablation (RFCA) in patients with VT after SVR. Methods: Twelve (3%) of 416 patients referred for RFCA for VT after myocardial infarction in three centers had undergone SVR. After induct... Abstract
Cited 2 times since 2011 (0.2 per year) source: EuropePMC
The Cochrane database of systematic reviews, Issue 5, 11 2 2011, Pages CD008128 Treatment of valvular heart disease during pregnancy for improving maternal and neonatal outcome. Henriquez DD, Roos-Hesselink JW, Schalij MJ, Klautz RJ, Helmerhorst FM, de Groot CJ
Background: Valvular heart disease constitutes the majority of all causes of heart disease in pregnancy. In the presence of valvular heart disease, the necessary haemodynamic changes of pregnancy might cause heart failure, leading to severe maternal and fetal morbidity and even mortality. Treatment of valvular heart disease is indicated when patients experience a deterioration of symptoms and in case of a severe valvular lesion. Whether medical therapy or interventional therapy is the optimal tr... Abstract
Cited 5 times since 2011 (0.4 per year) source: EuropePMC
Transfusion medicine (Oxford, England), Volume 21, Issue 4, 24 4 2011, Pages 236-246 The effect of RBC transfusions on cytokine gene expression after cardiac surgery in patients developing post-operative multiple organ failure. Sitniakowsky LS, Later AF, van de Watering LM, Bogaerts M, Brand A, Klautz RJ, Smit NP, van Hilten JA
Aim: To determine the effect of red blood cell (RBC) transfusions during cardiac surgery on cytokine gene expression (GE) in relation to multiple organ failure (MOF) development after systemic inflammatory response syndrome (SIRS). Background: RBC transfusion in cardiac surgery patients is dose-dependently associated with post-operative MOF, possibly acting as a second hit after cardiopulmonary bypass. Methods: For this observational study, 29 patients divided into four groups of cardiac surgery... Abstract
Cited 13 times since 2011 (1 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 142, Issue 3, 12 2 2011, Pages e93-100 Cardiac support device, restrictive mitral valve annuloplasty, and optimized medical treatment: a multimodality approach to nonischemic cardiomyopathy. Braun J, Ciarka A, Versteegh MI, Delgado V, Boersma E, Verwey HF, Schalij MJ, Bax JJ, Dion RA, van de Veire NR, Klautz RJ
Objective: Nonischemic dilated cardiomyopathy with functional mitral regurgitation carries a poor prognosis. Mitral valve surgery with implantation of a cardiac support device can treat mitral regurgitation and promote left ventricular reverse remodeling. This observational study evaluates clinical and echocardiographic outcomes of an individualized medico-surgical approach, focusing on mitral regurgitation recurrence and left ventricular reverse remodeling. Methods: Sixty-nine consecutive patie... Abstract
Cited 7 times since 2011 (0.5 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 27, Issue 8, 26 4 2011, Pages 1179-1193 Role of computed tomography imaging for transcatheter valvular repair/insertion. Ewe SH, Klautz RJ, Schalij MJ, Delgado V
During the last decade, the development of transcatheter based therapies has provided feasible therapeutic options for patients with symptomatic severe valvular heart disease who are deemed inoperable. The promising results of many nonrandomized series and recent landmark trials have increased the number of percutaneous transcatheter valve procedures in high operative risk patients. Pre-procedural imaging of the anatomy of the aortic or mitral valve and their spatial relationships is crucial to... Abstract
Cited 19 times since 2011 (1.4 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 91, Issue 2, 1 1 2011, Pages 491-498 Surgical ventricular restoration for patients with ischemic heart failure: determinants of two-year survival. Witkowski TG, ten Brinke EA, Delgado V, Ng AC, Bertini M, Marsan NA, Ewe SH, Auger D, Yiu KH, Braun J, Klein P, Steendijk P, Versteegh MI, Klautz RJ, Bax JJ
Background: Surgical ventricular restoration (SVR) improves left ventricular (LV) systolic function by partially restoring the normal geometry of the left ventricle. However, the beneficial effects of this surgical procedure on long-term clinical outcome remain controversial. The present study aimed to evaluate the independent determinants of 2-year morbidity and mortality rates after SVR. Methods: Seventy-nine patients with ischemic heart disease and LV ejection fraction of 0.35 or less were in... Abstract
Cited 22 times since 2011 (1.7 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 91, Issue 1, 1 1 2011, Pages 113-121 Three-dimensional echocardiography for the preoperative assessment of patients with left ventricular aneurysm. Marsan NA, Westenberg JJ, Roes SD, van Bommel RJ, Delgado V, van der Geest RJ, de Roos A, Klautz RJ, Reiber JC, Bax JJ
Background: Surgical ventricular reconstruction has been proposed as a treatment option in heart failure patients with left ventricular (LV) aneurysm. The feasibility of this procedure has some limitations, and extensive preoperative evaluation is necessary to give the correct indication. For this purpose, magnetic resonance imaging (MRI) is currently considered the gold standard, providing accurate quantification of LV shape, size, and global and regional function together with the assessment o... Abstract
Cited 16 times since 2010 (1.2 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 90, Issue 6, 1 1 2010, Pages 1913-1920 Clinical and functional effects of restrictive mitral annuloplasty at midterm follow-up in heart failure patients. ten Brinke EA, Klautz RJ, Tulner SA, Verwey HF, Bax JJ, Delgado V, Holman ER, Schalij MJ, van der Wall EE, Braun J, Versteegh MI, Dion RA, Steendijk P
Background: Restrictive mitral annuloplasty (RMA) is increasingly applied to treat functional mitral regurgitation in heart failure patients. Previous studies indicated beneficial clinical effects with low recurrence rates. However, the underlying pathophysiology is complex and outcome in terms of left ventricular function is not well known. We investigated chronic effects of RMA on ventricular function in relation to clinical outcome. Methods: Heart failure patients (n = 11) with severe mitral... Abstract
Cited 18 times since 2010 (1.3 per year) source: EuropePMC
Pain medicine (Malden, Mass.), Volume 11, Issue 11, 1 1 2010, Pages 1628-1634 Pain symptoms accompanying chronic poststernotomy pain: a pilot study. van Leersum NJ, van Leersum RL, Verwey HF, Klautz RJ
Objective: Despite the technical developments in surgical procedures, chronic poststernotomy pain (CPSP) is still very common. Many theories for its cause have been proposed in the literature, but the etiology is still not clear. Pain along the sternal scar and in the upper extremities (sometimes accompanied with paresthesia) persists in about 30% of cases. These symptoms have been regarded as two separate complications. This study investigated all pain symptoms in patients following sternotomy.... Abstract
Cited 88 times since 2010 (6.5 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 141, Issue 6, 15 3 2010, Pages 1431-1439 Tricuspid annuloplasty prevents right ventricular dilatation and progression of tricuspid regurgitation in patients with tricuspid annular dilatation undergoing mitral valve repair. Van de Veire NR, Braun J, Delgado V, Versteegh MI, Dion RA, Klautz RJ, Bax JJ
Objectives: We hypothesize that concomitant tricuspid annuloplasty in patients with tricuspid annular dilatation who undergo mitral valve repair could prevent progression of tricuspid regurgitation and right ventricular remodeling. Methods: In 2002, 80 patients underwent mitral valve repair. Concomitant tricuspid annuloplasty was performed in 13 patients with grade 3 or 4 tricuspid regurgitation. In 2004, 102 patients underwent mitral valve repair. Concomitant tricuspid annuloplasty was performe... Abstract
Cited 43 times since 2010 (3.1 per year) source: EuropePMC
Circulation, Volume 121, Issue 17, 19 3 2010, Pages 1887-1895 Early reperfusion during acute myocardial infarction affects ventricular tachycardia characteristics and the chronic electroanatomic and histological substrate. Wijnmaalen AP, Schalij MJ, von der Thüsen JH, Klautz RJ, Zeppenfeld K
Background: Reperfusion therapy during acute myocardial infarction results in myocardial salvage and improved ventricular function but may also influence the arrhythmogenic substrate for ventricular tachycardia (VT). This study used electroanatomic mapping and infarct histology to assess the impact of reperfusion on the substrate and on VT characteristics late after acute myocardial infarction. Methods and results: The study population consisted of 36 patients (32 men; age, 63+/-15 years) referr... Abstract
Cited 15 times since 2010 (1.1 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 140, Issue 6, 9 2 2010, Pages 1338-1344 Long-term effects of surgical ventricular restoration with additional restrictive mitral annuloplasty and/or coronary artery bypass grafting on left ventricular function: six-month follow-up by pressure-volume loops. ten Brinke EA, Klautz RJ, Tulner SA, Verwey HF, Bax JJ, Schalij MJ, van der Wall EE, Versteegh MI, Dion RA, Steendijk P
Objectives: Previous studies demonstrated beneficial short-term effects of surgical ventricular restoration on mechanical dyssynchrony and left ventricular function and improved midterm and long-term clinical parameters. However, long-term effects on systolic and diastolic left ventricular function are still largely unknown. Methods: We studied 9 patients with ischemic dilated cardiomyopathy who underwent surgical ventricular restoration with additional restrictive mitral annuloplasty and/or cor... Abstract
Cited 14 times since 2010 (1 per year) source: Scopus
JACC. Cardiovascular imaging, Volume 3, Issue 2, 1 1 2010, Pages 222-223 Successful transapical transcatheter valve implantation within a dysfunctional mitral bioprosthesis. de Weger A, Tavilla G, Ng AC, Delgado V, van der Kley F, Schuijf JD, Bax JJ, Klautz RJ
Cited 9 times since 2010 (0.6 per year) source: EuropePMC
The Journal of thoracic and cardiovascular surgery, Volume 140, Issue 4, 1 1 2010, Pages 807-815 Noninvasive estimation of left ventricular filling pressures in patients with heart failure after surgical ventricular restoration and restrictive mitral annuloplasty. ten Brinke EA, Bertini M, Klautz RJ, Antoni ML, Holman ER, van de Veire NR, Bax JJ, Steendijk P
Objective: Doppler echocardiography, including tissue Doppler imaging, is widely applied to assess diastolic left ventricular function using early transmitral flow velocity combined with mitral annular velocity as a noninvasive estimate of left ventricular filling pressures. However, the accuracy of early transmitral flow velocity/mitral annular velocity in patients with heart failure, particularly after extensive cardiac surgery, is debated. Global diastolic strain rate during isovolumic relaxa... Abstract
Cited 1 times since 2010 (0.1 per year) source: EuropePMC
Innovations (Philadelphia, Pa.), Volume 5, Issue 1, 1 1 2010, Pages 16-21 Resizable ventricular patch plasty in the porcine left ventricle: a pilot study. Huijgen WH, Gründeman PF, van der Spoel T, Cramer MJ, Steendijk P, Klautz RJ, van Herwerden LA
Objective: : Endoventricular circular patch plasty is a method used to reconstruct the ventricular cavity in patients with (post) ischemic left ventricular aneurysm or global dilatation. However, late redilatation with mitral regurgitation has been reported, in which postoperative apex shape seems to play an important role. We studied the feasibility of ventricular volume downsizing with a variably shaped patch in porcine hearts. Methods: : In five in vitro and two acute animal experiments, a dy... Abstract
Cited 140 times since 2009 (9.7 per year) source: EuropePMC
European heart journal, Volume 30, Issue 24, 1 1 2009, Pages 3037-3047 Strain analysis in patients with severe aortic stenosis and preserved left ventricular ejection fraction undergoing surgical valve replacement. Delgado V, Tops LF, van Bommel RJ, van der Kley F, Marsan NA, Klautz RJ, Versteegh MI, Holman ER, Schalij MJ, Bax JJ
Aims: To evaluate myocardial multidirectional strain and strain rate (S-and-SR) in severe aortic stenosis (AS) patients with preserved left ventricular (LV) ejection fraction (EF), using two-dimensional speckle-tracking strain imaging (2D-STI). The long-term effect of aortic valve replacement (AVR) on S-and-SR was also evaluated. Methods and results: Changes in LV radial, circumferential, and longitudinal S-and-SR were evaluated in 73 severe AS patients (65 +/- 13 years; aortic valve area 0.8 +/... Abstract
Cited 24 times since 2009 (1.7 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 96, Issue 3, 28 4 2009, Pages 213-219 Single-beat estimation of the left ventricular end-diastolic pressure-volume relationship in patients with heart failure. Ten Brinke EA, Burkhoff D, Klautz RJ, Tschöpe C, Schalij MJ, Bax JJ, van der Wall EE, Dion RA, Steendijk P
Aims: To test a method to predict the end-diastolic pressure-volume relationship (EDPVR) from a single beat in patients with heart failure. Methods and results: Patients (New York Heart Association class III-IV) scheduled for mitral annuloplasty (n=9) or ventricular restoration (n=10) and patients with normal left ventricular function undergoing coronary artery bypass grafting (n=12) were instrumented with pressure-conductance catheters to measure pressure-volume loops before and after surgery.... Abstract
The Journal of thoracic and cardiovascular surgery, Volume 140, Issue 1, 26 4 2009, Pages 240-241 Balloon sizing in surgical ventricular restoration: what volume are we targeting? ten Brinke EA, Klautz RJ, Steendijk P