65 results
ESC heart failure,
Volume 9, Issue 3, 30 5 2022, Pages 2007-2012
The first experience with sodium-glucose cotransporter 2 inhibitor for the treatment of systemic right ventricular failure.
Egorova AD, Nederend M, Tops LF, Vliegen HW, Jongbloed MRM, Kiès P
In congenitally corrected transposition of the great arteries, the morphological right ventricle supports the systemic circulation. This chronic exposure to pressure overload ultimately leads to systemic right ventricular (sRV) dysfunction and heart failure. Pharmacological options for the treatment of sRV failure are poorly defined and no solid recommendations are made in the most recent guidelines. Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are a new class of antihyperglycaemic drugs t...
Abstract
European heart journal. Case reports,
Volume 6, Issue 2, 16 3 2022, Pages ytac067
Case report of the broad spectrum of late complications in an adult patient with univentricular physiology palliated by the Fontan circulation.
Nederend M, Egorova AD, Vliegen HW, Roest AAW, Ruijter BN, Korteweg T, Ninaber MK, Zeppenfeld K, Hazekamp MG, Kiès P, Jongbloed MRM
Background: At the most severe end of the spectrum of congenital heart disease are patients with an univentricular physiology. They comprise a heterogeneous group of congenital heart malformations that have the common characteristic that the cardiac morphology is not equipped for sustaining a biventricular circulation. Case summary: Here, we present a case of an adult patient after Fontan palliation, illustrative of the complex clinical course and the broad spectrum of complications that can be...
Abstract
Cited 3 times since 2022 (10.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 3, 1 1 2022, Pages 412-422
The Leiden Convention coronary coding system: translation from the surgical to the universal view.
Koppel CJ, Vliegen HW, Bökenkamp R, Ten Harkel ADJ, Kiès P, Egorova AD, Jukema JW, Hazekamp MG, Schalij MJ, Gittenberger-de Groot AC, Jongbloed MRM
Aims: The Leiden Convention coronary coding system structures the large variety of coronary anatomical patterns; isolated and in congenital heart disease. It is widely used by surgeons but not by cardiologists as the system uses a surgeons' cranial view. Since thoracic surgeons and cardiologists work closely together, a coronary coding system practical for both disciplines is mandatory. To this purpose, the 'surgical' coronary coding system was adapted to an 'imaging' sy...
Abstract
Frontiers in cardiovascular medicine,
Volume 9, 31 5 2022, Pages 793972
Hybrid CMR- and FDG-PET-Imaging Gives New Insights Into the Relationship of Myocardial Metabolic Activity and Fibrosis in Patients With Becker Muscular Dystrophy.
Vehof V, Büther F, Florian A, Drakos S, Chamling B, Kies P, Stegger L, Yilmaz A
Background: Cardiac involvement in patients with Becker muscular dystrophy (BMD) is an important predictor of mortality. The cardiac phenotype of BMD patients is characterized by slowly progressive myocardial fibrosis that starts in the left ventricular (LV) free wall segments and extends into the septal wall during the disease course. Purpose: Since the reason for this characteristic cardiac phenotype is unknown and comprehensive approaches using e.g. hybrid imaging combining cardiovascular mag...
Abstract
Cited 1 times since 2022 (2.7 per year)
source: EuropePMC
European heart journal. Cardiovascular pharmacotherapy,
Volume 8, Issue 1, 1 1 2022, Pages 77-84
Medication in adults after atrial switch for transposition of the great arteries: clinical practice and recommendations.
Woudstra OI, Kuijpers JM, Jongbloed MRM, van Dijk APJ, Sieswerda GT, Vliegen HW, Egorova AD, Kiès P, Duijnhouwer AL, Robbers-Visser D, Konings TC, Zwinderman AH, Meijboom FJ, Mulder BJM, Bouma BJ
Aims: Heart failure is the main threat to long-term health in adults with transposition of the great arteries (TGA) corrected by an atrial switch operation (AtrSO). Current guidelines refrain from recommending heart failure medication in TGA-AtrSO, as there is insufficient data to support the hypothesis that it is beneficial. Medication is therefore prescribed based on personal judgements. We aimed to evaluate medication use in TGA-AtrSO patients and examine the association of use of renin-angio...
Abstract
Cited 1 times since 2021 (1.5 per year)
source: EuropePMC
Frontiers in physiology,
Volume 12, 16 3 2021, Pages 665298
Asymmetry and Heterogeneity: Part and Parcel in Cardiac Autonomic Innervation and Function.
Zandstra TE, Notenboom RGE, Wink J, Kiès P, Vliegen HW, Egorova AD, Schalij MJ, De Ruiter MC, Jongbloed MRM
The cardiac autonomic nervous system (cANS) regulates cardiac adaptation to different demands. The heart is an asymmetrical organ, and in the selection of adequate treatment of cardiac diseases it may be relevant to take into account that the cANS also has sidedness as well as regional differences in anatomical, functional, and molecular characteristics. The left and right ventricles respond differently to adrenergic stimulation. Isoforms of nitric oxide synthase, which plays an important role i...
Abstract
Cited 1 times since 2021 (1.4 per year)
source: EuropePMC
Journal of cardiovascular development and disease,
Volume 8, Issue 9, 26 4 2021, Pages 102
The Coronary Arteries in Adults after the Arterial Switch Operation: A Systematic Review.
Engele LJ, Mulder BJM, Schoones JW, Kiès P, Egorova AD, Vliegen HW, Hazekamp MG, Bouma BJ, Jongbloed MRM
Coronary artery status in adults long after the arterial switch operation (ASO) is unclear. We conducted a systematic review to provide an overview of coronary complications during adulthood and to evaluate the value of routine coronary imaging in adults after ASO, in light of current guidelines. Articles were screened for the inclusion of adult ASO patients and data on coronary complications and findings of coronary imaging were collected. A total of 993 adults were followed with a median avail...
Abstract
Frontiers in cardiovascular medicine,
Volume 8, 24 4 2021, Pages 668503
Computed Tomography Derived Coronary Triangulated Orifice Area-Deduction of a New Parameter for Follow-up After Surgical Correction of Anomalous Aortic Origin of Coronary Arteries and Call for Validation.
Meijer FMM, Kiès P, Verheijen DBH, Vliegen HW, Jongbloed MRM, Hazekamp MG, Lamb HJ, Egorova AD
Introduction: Anomalous aortic origin of a coronary artery (AAOCA) from the opposite sinus of Valsalva is a rare congenital abnormality. Computed tomography angiography (CTA) is primarily used as a diagnostic tool to evaluate the anatomy and identify potentially malignant AAOCA variants. Limited data is available on the role of CTA during postoperative follow-up. We aimed to develop an objective CTA derived parameter for diagnostic evaluation and follow-up after surgical correction of AAOCA and...
Abstract
Frontiers in cardiovascular medicine,
Volume 8, 16 3 2021, Pages 644193
Validation and Feasibility of Echocardiographic Assessment of Systemic Right Ventricular Function: Serial Correlation With MRI.
Zandstra TE, Jongbloed MRM, Widya RL, Ten Harkel ADJ, Holman ER, Mertens BJA, Vliegen HW, Egorova AD, Schalij MJ, Kiès P
Background: Inherent to its geometry, echocardiographic imaging of the systemic right ventricle (RV) is challenging. Therefore, echocardiographic assessment of systemic RV function may not always be feasible and/or reproducible in daily practice. Here, we aim to validate the usefulness of a comprehensive range of 32 echocardiographic measurements of systemic RV function in a longitudinal cohort by serial assessment of their correlations with cardiac magnetic resonance (CMR)-derived systemic RV e...
Abstract
Cited 3 times since 2021 (2.5 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 29, Issue 6, 8 2 2021, Pages 311-317
The first multicentre study on coronary anomalies in the Netherlands: MuSCAT.
Koppel CJ, Driesen BW, de Winter RJ, van den Bosch AE, van Kimmenade R, Wagenaar LJ, Jukema JW, Hazekamp MG, van der Kley F, Jongbloed MRM, Kiès P, Egorova AD, Verheijen DBH, Damman P, Schoof PH, Wilschut J, Stoel M, Speekenbrink RGH, Voskuil M, Vliegen HW
Background: Current guidelines on coronary anomalies are primarily based on expert consensus and a limited number of trials. A gold standard for diagnosis and a consensus on the treatment strategy in this patient group are lacking, especially for patients with an anomalous origin of a coronary artery from the opposite sinus of Valsalva (ACAOS) with an interarterial course. Aim: To provide evidence-substantiated recommendations for diagnostic work-up, treatment and follow-up of patients with anom...
Abstract
Open heart,
Volume 8, Issue 1, 1 1 2021, Pages e001252
Patient information portal for congenital aortic and pulmonary valve disease: a stepped-wedge cluster randomised trial.
Etnel JRG, Bons LR, De Heer F, Robbers-Visser D, Van Beynum IM, Straver B, Jongbloed MR, Kiès P, Slieker MG, Van Dijk APJ, Kluin J, Bertels RA, Utens EMWJ, The R, Van Galen E, Mulder BJM, Blom NA, Hazekamp MG, Roos-Hesselink JW, Helbing WA, Bogers AJJC, Takkenberg JJM
In response to an increased need for patient information in congenital heart disease, we previously developed an online, evidence-based information portal for patients with congenital aortic and pulmonary valve disease. To assess its effectiveness, a stepped-wedge cluster randomised trial was conducted. Adult patients and caregivers of paediatric patients with congenital aortic and/or pulmonary valve disease and/or tetralogy of Fallot who visited the outpatient clinic at any of the four particip...
Abstract
Cited 2 times since 2021 (1.6 per year)
source: EuropePMC
Journal of cardiovascular development and disease,
Volume 8, Issue 3, 26 4 2021, Pages 25
The Clinical Spectrum of Kommerell's Diverticulum in Adults with a Right-Sided Aortic Arch: A Case Series and Literature Overview.
van Rosendael PJ, Stöger JL, Kiès P, Vliegen HW, Hazekamp MG, Koolbergen DR, Lamb HJ, Jongbloed MRM, Egorova AD
Kommerell's diverticulum is a rare vascular anomaly characterized as an outpouch at the onset of an aberrant subclavian artery. In the variant of a right-sided aortic arch, the trachea and esophagus are enclosed dorsally by the arch. In the configuration of an aberrant left subclavian artery, a Kommerell's diverticulum and persisting ductus arteriosus or ductal ligament enclose the lateral side, forming a vascular ring which may result in (symptomatic) esophageal or tracheal compressio...
Abstract
Cited 1 times since 2021 (0.8 per year)
source: EuropePMC
Journal of the American Heart Association,
Volume 10, Issue 5, 22 4 2021, Pages e018565
Clinical Course Long After Atrial Switch: A Novel Risk Score for Major Clinical Events.
Woudstra OI, Zandstra TE, Vogel RF, van Dijk APJ, Vliegen HW, Kiès P, Jongbloed MRM, Egorova AD, Doevendans PAFM, Konings TC, Mulder BJM, Tanck MWT, Meijboom FJ, Bouma BJ
Background Patients with transposition of the great arteries corrected by an atrial switch operation experience major clinical events during adulthood, mainly heart failure (HF) and arrhythmias, but data on the emerging risks remain scarce. We assessed the risk for events during the clinical course in adulthood, and provided a novel risk score for event-free survival. Methods and Results This multicenter study observed 167 patients with transposition of the great arteries corrected by an atrial...
Abstract
Cited 1 times since 2021 (0.7 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 107, Issue 21, 15 3 2021, Pages 1725-1730
Sacubitril/valsartan in the treatment of systemic right ventricular failure.
Zandstra TE, Nederend M, Jongbloed MRM, Kiès P, Vliegen HW, Bouma BJ, Tops LF, Schalij MJ, Egorova AD
Objective: Pharmacological options for patients with a failing systemic right ventricle (RV) in the context of transposition of the great arteries (TGA) after atrial switch or congenitally corrected TGA (ccTGA) are not well defined. This study aims to investigate the feasibility and effects of sacubitril/valsartan treatment in a single-centre cohort of patients. Methods: Data on all consecutive adult patients (n=20, mean age 46 years, 50% women) with a failing systemic RV in a biventricular circ...
Abstract
Cited 1 times since 2021 (0.7 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 32, Issue 1, 1 1 2021, Pages 122-129
The significance of symptoms before and after surgery for anomalous aortic origin of coronary arteries in adolescents and adults.
Meijer FMM, Egorova AD, Jongbloed MRM, Koppel C, Habib G, Hazekamp MG, Vliegen HW, Kies P
Objectives: The aim of this study is to describe the significance of symptoms preoperatively and at medium-term follow-up in adolescent and adult patients who underwent surgery of anomalous aortic origin of a coronary artery (AAOCA). Methods: Consecutive patients who underwent surgery for AAOCA in our tertiary referral centre between 2001 and 2018 were included. Clinical characteristics and symptoms were evaluated and medium-term outcomes were recorded. Symptoms were classified according to the...
Abstract
European heart journal. Case reports,
Volume 4, Issue 5, 15 3 2020, Pages 1-3
Pulmonary hypertension causing left main coronary artery compression.
Verheijen DBH, Meijer FMM, Kiès P, Egorova AD
Abstract
Clinical case reports,
Volume 8, Issue 11, 6 1 2020, Pages 2320-2321
The constrictive consequences of pericardial calcifications.
Egorova AD, Schalij MJ, Kiès P
A 53-year-old man presented with symptomatic severe pulmonary valve regurgitation. He underwent a diagnostic catheterization. A heavily calcified pericardium and the pressure tracings illustrate typical features of constrictive pericarditis physiology, including the "square root sign." This condition is important to recognize given the progressive nature and poor prognosis if untreated.
Abstract
Journal of cardiology,
Volume 76, Issue 5, 19 3 2020, Pages 514-520
QT interval variability and heart rate turbulence are associated with clinical characteristics in congenital heart disease patients with a systemic right ventricle.
Zandstra T, Kiès P, Man SC, Maan A, Bootsma M, Vliegen H, Egorova A, Holman E, Schalij M, Jongbloed M
Background: QT interval variability (QTV) and heart rate turbulence (HRT) are measures of cardiac autonomic function, which, when abnormal, are correlated with ventricular arrhythmias and worse clinical outcome. This study aims to evaluate QTV and HRT in patients with a systemic right ventricle (RV) and to assess correlations with clinical characteristics. Methods: In a retrospective cohort study, QTV and HRT were derived from 24-h Holter registrations of patients with a systemic RV and healthy...
Abstract
Cited 3 times since 2020 (1.6 per year)
source: EuropePMC
Autonomic neuroscience : basic & clinical,
Volume 227, 26 4 2020, Pages 102696
Association between reduced heart rate variability components and supraventricular tachyarrhythmias in patients with a systemic right ventricle.
Zandstra T, Kiès P, Maan A, Man SC, Bootsma M, Vliegen H, Egorova A, Mertens B, Holman E, Schalij M, Jongbloed M
Background: Patients with a systemic right ventricle are prone to develop heart failure. Abnormal heart rate variability (HRV), a measure of autonomic dysfunction, is associated with morbidity and mortality in patients with left ventricular failure. The association between HRV and supraventricular arrhythmias (SVTs), which are associated with adverse events in this population, was assessed. Methods: 24-Hour Holter recordings of patients with a systemic right ventricle and healthy controls were a...
Abstract
Journal of electrocardiology,
Volume 61, 5 1 2020, Pages 141-146
Lack of diagnostic utility of the ECG-derived ventricular gradient in patients with suspected acute pulmonary embolism.
Meijer FMM, Hendriks SV, Huisman MV, van der Hulle T, Swenne CA, Kies P, Jongbloed MRM, Egorova AD, Vliegen HW, Klok FA
Introduction: The YEARS algorithm was successfully developed to reduce the number of computed tomography pulmonary angiography (CTPA) investigations in the diagnostic management of patients with suspected pulmonary embolism (PE), although half of patients still needed to be referred for CTPA. We hypothesized that ECG derived ventricular gradient optimized for right ventricular pressure overload (VG-RVPO), an easy to use tool for detecting PE-induced pulmonary hypertension (PH), may further impro...
Abstract
