Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
61 results
Cited 5 times since 2022 (2.6 per year) source: EuropePMC
Frontiers in cardiovascular medicine, Volume 9, 6 1 2022, Pages 883873 Performance of a HeartLogic<sup>TM</sup> Based Care Path in the Management of a Real-World Chronic Heart Failure Population. Feijen M, Egorova AD, Treskes RW, Mertens BJA, Jukema JW, Schalij MJ, Beeres SLMA
Aim: Early detection of impending fluid retention and timely adjustment of (medical) therapy can prevent heart failure related hospitalizations. The multisensory cardiac implantable electronic device (CIED) based algorithm HeartLogicTM aims to alert in case of impending fluid retention. The aim of the current analysis is to evaluate the performance of the HeartLogicTM guided heart failure care path in a real-world heart failure population and to investigate whether the height of the index and th... Abstract
Cited 1 times since 2022 (0.5 per year) source: EuropePMC
European heart journal open, Volume 2, Issue 4, 2 1 2022, Pages oeac031 A comprehensive analysis of the intramural segment in interarterial anomalous coronary arteries using computed tomography angiography. Koppel CJ, Verheijen DBH, Kiès P, Egorova AD, Lamb HJ, Voskuil M, Jukema JW, Koolbergen DR, Hazekamp MG, Schalij MJ, Jongbloed MRM, Vliegen HW
Aims: An anomalous coronary artery originating from the opposite sinus of Valsalva (ACAOS) with an interarterial course can be assessed using computed tomography angiography (CTA) for the presence of high-risk characteristics associated with sudden cardiac death. These features include a slit-like ostium, acute angle take-off, proximal luminal narrowing, and an intramural segment. To date, no robust CTA criteria exist to determine the presence of an intramural segment. We aimed to deduct new CTA... Abstract
Cited 7 times since 2022 (3.4 per year) source: EuropePMC
ESC heart failure, Volume 9, Issue 3, 30 5 2022, Pages 2007-2012 The first experience with sodium-glucose cotransporter 2 inhibitor for the treatment of systemic right ventricular failure. Egorova AD, Nederend M, Tops LF, Vliegen HW, Jongbloed MRM, Kiès P
In congenitally corrected transposition of the great arteries, the morphological right ventricle supports the systemic circulation. This chronic exposure to pressure overload ultimately leads to systemic right ventricular (sRV) dysfunction and heart failure. Pharmacological options for the treatment of sRV failure are poorly defined and no solid recommendations are made in the most recent guidelines. Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are a new class of antihyperglycaemic drugs t... Abstract
Cited 2 times since 2022 (0.9 per year) source: EuropePMC
European journal of cardiovascular nursing, Volume 21, Issue 2, 1 1 2022, Pages 169-173 Implantable cardioverter-defibrillators and the older patient: the Dutch clinical practice. Yilmaz D, Egorova AD, Schalij MJ, van Erven L
Background and objective: Balance between benefit and burden of implantable cardioverter-defibrillator (ICD) therapy is more debatable in older patients, compared to younger patients. Of around 6000 yearly implanted ICDs in the Netherlands, 1:4 is received by patients ≥75 years. We aimed to evaluate the current clinical practice in the Netherlands for ICD implants and generator replacements, with a special focus on the older ICD patients. Research design and methods: Cardiologists from all Dutch... Abstract
European heart journal. Case reports, Volume 6, Issue 3, 17 3 2022, Pages ytac087 Successful hybrid cardiac resynchronization therapy in a patient with failing systemic right ventricle and significant tricuspid regurgitation in transposition of the great arteries after atrial switch procedure according to Mustard. Nederend M, Zeppenfeld K, Jongbloed MRM, Egorova AD
Background: Patients with a systemic right ventricle (sRV) in the context of transposition of the great arteries (TGA) late after atrial switch are prone to heart failure. Complications like tricuspid valve regurgitation (TR) can further aggravate sRV dysfunction. Tricuspid valve regurgitation is usually secondary to annular dilatation and restriction. Criteria for cardiac resynchronization therapy (CRT) in this patient group are not well defined and should be considered on a case-by-case basis.... Abstract
Cited 2 times since 2022 (0.9 per year) source: EuropePMC
European heart journal. Case reports, Volume 6, Issue 2, 16 3 2022, Pages ytac067 Case report of the broad spectrum of late complications in an adult patient with univentricular physiology palliated by the Fontan circulation. Nederend M, Egorova AD, Vliegen HW, Roest AAW, Ruijter BN, Korteweg T, Ninaber MK, Zeppenfeld K, Hazekamp MG, Kiès P, Jongbloed MRM
Background: At the most severe end of the spectrum of congenital heart disease are patients with an univentricular physiology. They comprise a heterogeneous group of congenital heart malformations that have the common characteristic that the cardiac morphology is not equipped for sustaining a biventricular circulation. Case summary: Here, we present a case of an adult patient after Fontan palliation, illustrative of the complex clinical course and the broad spectrum of complications that can be... Abstract
Cited 8 times since 2022 (3.6 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 23, Issue 3, 1 1 2022, Pages 412-422 The Leiden Convention coronary coding system: translation from the surgical to the universal view. Koppel CJ, Vliegen HW, Bökenkamp R, Ten Harkel ADJ, Kiès P, Egorova AD, Jukema JW, Hazekamp MG, Schalij MJ, Gittenberger-de Groot AC, Jongbloed MRM
Aims: The Leiden Convention coronary coding system structures the large variety of coronary anatomical patterns; isolated and in congenital heart disease. It is widely used by surgeons but not by cardiologists as the system uses a surgeons' cranial view. Since thoracic surgeons and cardiologists work closely together, a coronary coding system practical for both disciplines is mandatory. To this purpose, the 'surgical' coronary coding system was adapted to an 'imaging' sy... Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 30, Issue 2, 3 1 2022, Pages 76-83 No substantial excess all-cause mortality among cardiac implantable electronic device patients during the first COVID‑19 lockdown in the Leiden area. Feijen M, Egorova AD, van der Velde ET, Schalij MJ, Beeres SLMA
In the Netherlands, the coronavirus disease 2019 (COVID‑19) pandemic has resulted in excess mortality nationwide. Chronic heart disease patients are at risk for a complicated COVID‑19 course. The current study investigates all-cause mortality among cardiac implantable electronic device (CIED) patients during the first peak of the pandemic and compares the data to the statistics for the corresponding period in the two previous years. Data of adult CIED patients undergoing follow-up at the Leiden... Abstract
Cited 2 times since 2022 (0.9 per year) source: EuropePMC
European heart journal. Cardiovascular pharmacotherapy, Volume 8, Issue 1, 1 1 2022, Pages 77-84 Medication in adults after atrial switch for transposition of the great arteries: clinical practice and recommendations. Woudstra OI, Kuijpers JM, Jongbloed MRM, van Dijk APJ, Sieswerda GT, Vliegen HW, Egorova AD, Kiès P, Duijnhouwer AL, Robbers-Visser D, Konings TC, Zwinderman AH, Meijboom FJ, Mulder BJM, Bouma BJ
Aims: Heart failure is the main threat to long-term health in adults with transposition of the great arteries (TGA) corrected by an atrial switch operation (AtrSO). Current guidelines refrain from recommending heart failure medication in TGA-AtrSO, as there is insufficient data to support the hypothesis that it is beneficial. Medication is therefore prescribed based on personal judgements. We aimed to evaluate medication use in TGA-AtrSO patients and examine the association of use of renin-angio... Abstract
Cited 16 times since 2021 (6.2 per year) source: EuropePMC
Frontiers in physiology, Volume 12, 16 3 2021, Pages 665298 Asymmetry and Heterogeneity: Part and Parcel in Cardiac Autonomic Innervation and Function. Zandstra TE, Notenboom RGE, Wink J, Kiès P, Vliegen HW, Egorova AD, Schalij MJ, De Ruiter MC, Jongbloed MRM
The cardiac autonomic nervous system (cANS) regulates cardiac adaptation to different demands. The heart is an asymmetrical organ, and in the selection of adequate treatment of cardiac diseases it may be relevant to take into account that the cANS also has sidedness as well as regional differences in anatomical, functional, and molecular characteristics. The left and right ventricles respond differently to adrenergic stimulation. Isoforms of nitric oxide synthase, which plays an important role i... Abstract
Cited 4 times since 2021 (1.5 per year) source: EuropePMC
Journal of cardiovascular development and disease, Volume 8, Issue 9, 26 4 2021, Pages 102 The Coronary Arteries in Adults after the Arterial Switch Operation: A Systematic Review. Engele LJ, Mulder BJM, Schoones JW, Kiès P, Egorova AD, Vliegen HW, Hazekamp MG, Bouma BJ, Jongbloed MRM
Coronary artery status in adults long after the arterial switch operation (ASO) is unclear. We conducted a systematic review to provide an overview of coronary complications during adulthood and to evaluate the value of routine coronary imaging in adults after ASO, in light of current guidelines. Articles were screened for the inclusion of adult ASO patients and data on coronary complications and findings of coronary imaging were collected. A total of 993 adults were followed with a median avail... Abstract
European heart journal. Case reports, Volume 5, Issue 9, 17 3 2021, Pages ytab335 Fusion cardiac resynchronization therapy in an left ventricular assist device patient from two devices and crossing leads: a case report. Egorova AD, van Erven L, Beeres SLMA, Tops LF
Background: Cardiac implanted electronic devices (CIED) have significantly improved the survival and quality of life in heart failure patients. Although implantable cardioverter-defibrillators (ICD) and cardiac resynchronization therapy (CRT) have a major role in patients with moderate to severe heart failure symptoms, the role of these devices in patients with a left ventricular assist device (LVAD) is not yet well defined. The burden of CIED-related procedures in patients with an LVAD is high.... Abstract
Cited 1 times since 2021 (0.4 per year) source: EuropePMC
Frontiers in cardiovascular medicine, Volume 8, 24 4 2021, Pages 668503 Computed Tomography Derived Coronary Triangulated Orifice Area-Deduction of a New Parameter for Follow-up After Surgical Correction of Anomalous Aortic Origin of Coronary Arteries and Call for Validation. Meijer FMM, Kiès P, Verheijen DBH, Vliegen HW, Jongbloed MRM, Hazekamp MG, Lamb HJ, Egorova AD
Introduction: Anomalous aortic origin of a coronary artery (AAOCA) from the opposite sinus of Valsalva is a rare congenital abnormality. Computed tomography angiography (CTA) is primarily used as a diagnostic tool to evaluate the anatomy and identify potentially malignant AAOCA variants. Limited data is available on the role of CTA during postoperative follow-up. We aimed to develop an objective CTA derived parameter for diagnostic evaluation and follow-up after surgical correction of AAOCA and... Abstract
European heart journal, Volume 42, Issue 18, 1 1 2021, Pages 1811 A case of tortuous anatomy: cervical aortic arch. van Driest FY, Stöger JL, Scholte AJHA, Jukema JW, Egorova AD
Cited 3 times since 2021 (1 per year) source: EuropePMC
European heart journal. Case reports, Volume 5, Issue 4, 12 2 2021, Pages ytab068 Failing systemic right ventricle in a patient with dextrocardia and complex congenitally corrected transposition of the great arteries: a case report of successful transvenous cardiac resynchronization therapy. Nederend M, van Erven L, Zeppenfeld K, Vliegen HW, Egorova AD
Background: Patients with congenitally corrected transposition of the great arteries (ccTGA) are prone to the development of advanced atrio-ventricular block requiring chronic ventricular pacing. The morphological right ventricle (RV) often develops systolic dysfunction as it is unable to withstand the chronic pressure overload it is exposed to when supporting the systemic circulation. Case summary: A 56-year-old woman with dextrocardia and complex ccTGA with a history of dual-chamber implantabl... Abstract
Cited 1 times since 2021 (0.3 per year) source: EuropePMC
Frontiers in cardiovascular medicine, Volume 8, 16 3 2021, Pages 644193 Validation and Feasibility of Echocardiographic Assessment of Systemic Right Ventricular Function: Serial Correlation With MRI. Zandstra TE, Jongbloed MRM, Widya RL, Ten Harkel ADJ, Holman ER, Mertens BJA, Vliegen HW, Egorova AD, Schalij MJ, Kiès P
Background: Inherent to its geometry, echocardiographic imaging of the systemic right ventricle (RV) is challenging. Therefore, echocardiographic assessment of systemic RV function may not always be feasible and/or reproducible in daily practice. Here, we aim to validate the usefulness of a comprehensive range of 32 echocardiographic measurements of systemic RV function in a longitudinal cohort by serial assessment of their correlations with cardiac magnetic resonance (CMR)-derived systemic RV e... Abstract
Cited 6 times since 2021 (1.9 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 29, Issue 6, 8 2 2021, Pages 311-317 The first multicentre study on coronary anomalies in the Netherlands: MuSCAT. Koppel CJ, Driesen BW, de Winter RJ, van den Bosch AE, van Kimmenade R, Wagenaar LJ, Jukema JW, Hazekamp MG, van der Kley F, Jongbloed MRM, Kiès P, Egorova AD, Verheijen DBH, Damman P, Schoof PH, Wilschut J, Stoel M, Speekenbrink RGH, Voskuil M, Vliegen HW
Background: Current guidelines on coronary anomalies are primarily based on expert consensus and a limited number of trials. A gold standard for diagnosis and a consensus on the treatment strategy in this patient group are lacking, especially for patients with an anomalous origin of a coronary artery from the opposite sinus of Valsalva (ACAOS) with an interarterial course. Aim: To provide evidence-substantiated recommendations for diagnostic work-up, treatment and follow-up of patients with anom... Abstract
Cited 7 times since 2021 (2.2 per year) source: EuropePMC
Journal of cardiovascular development and disease, Volume 8, Issue 3, 26 4 2021, Pages 25 The Clinical Spectrum of Kommerell's Diverticulum in Adults with a Right-Sided Aortic Arch: A Case Series and Literature Overview. van Rosendael PJ, Stöger JL, Kiès P, Vliegen HW, Hazekamp MG, Koolbergen DR, Lamb HJ, Jongbloed MRM, Egorova AD
Background: Kommerell's diverticulum is a rare vascular anomaly characterized as an outpouch at the onset of an aberrant subclavian artery. In the variant of a right-sided aortic arch, the trachea and esophagus are enclosed dorsally by the arch. In the configuration of an aberrant left subclavian artery, a Kommerell's diverticulum and persisting ductus arteriosus or ductal ligament enclose the lateral side, forming a vascular ring which may result in (symptomatic) esophageal or trachea... Abstract
Cited 9 times since 2021 (2.8 per year) source: EuropePMC
Journal of the American Heart Association, Volume 10, Issue 5, 22 4 2021, Pages e018565 Clinical Course Long After Atrial Switch: A Novel Risk Score for Major Clinical Events. Woudstra OI, Zandstra TE, Vogel RF, van Dijk APJ, Vliegen HW, Kiès P, Jongbloed MRM, Egorova AD, Doevendans PAFM, Konings TC, Mulder BJM, Tanck MWT, Meijboom FJ, Bouma BJ
Background Patients with transposition of the great arteries corrected by an atrial switch operation experience major clinical events during adulthood, mainly heart failure (HF) and arrhythmias, but data on the emerging risks remain scarce. We assessed the risk for events during the clinical course in adulthood, and provided a novel risk score for event-free survival. Methods and Results This multicenter study observed 167 patients with transposition of the great arteries corrected by an atrial... Abstract
Cited 13 times since 2021 (4.1 per year) source: EuropePMC
ESC heart failure, Volume 8, Issue 2, 22 4 2021, Pages 1541-1551 Clinical and economic impact of HeartLogic™ compared with standard care in heart failure patients. Treskes RW, Beles M, Caputo ML, Cordon A, Biundo E, Maes E, Egorova AD, Schalij MJ, Van Bockstal K, Grazioli-Gauthier L, Vanderheyden M, Bartunek J, Auricchio A, Beeres SLMA, Heggermont WA
Aims: The implantable cardiac defibrillator/cardiac resynchronization therapy with defibrillator-based HeartLogic™ algorithm has recently been developed for early detection of impending decompensation in heart failure (HF) patients; but whether this novel algorithm can reduce HF hospitalizations has not been evaluated. We investigated if activation of the HeartLogic algorithm reduces the number of hospital admissions for decompensated HF in a 1 year post-activation period as compared with a 1 ye... Abstract