Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
36 results
BMJ open, Volume 13, Issue 6, 8 2 2023, Pages e071822 Ruling out acute coronary syndrome in primary care with a clinical decision rule and a capillary, high-sensitive troponin I point of care test: study protocol of a diagnostic RCT in the Netherlands (POB HELP). van den Bulk S, Petrus AHJ, Willemsen RTA, Boogers MJ, Meeder JG, Rahel BM, van den Akker-van Marle ME, Numans ME, Dinant GJ, Bonten TN
Introduction: Chest pain is a common reason for consultation in primary care. To rule out acute coronary syndrome (ACS), general practitioners (GP) refer 40%-70% of patients with chest pain to the emergency department (ED). Only 10%-20% of those referred, are diagnosed with ACS. A clinical decision rule, including a high-sensitive cardiac troponin-I point-of-care test (hs-cTnI-POCT), may safely rule out ACS in primary care. Being able to safely rule out ACS at the GP level reduces referrals and... Abstract
European heart journal. Digital health, Volume 4, Issue 4, 7 1 2023, Pages 347-356 Mobile health for cardiovascular risk management after cardiac surgery: results of a sub-analysis of The Box 2.0 study. Biersteker TE, Boogers MJ, Schalij MJ, Braun J, Groenwold RHH, Atsma DE, Treskes RW
Aims: Lowering low-density lipoprotein (LDL-C) and blood pressure (BP) levels to guideline recommended values reduces the risk of major adverse cardiac events in patients who underwent coronary artery bypass grafting (CABG). To improve cardiovascular risk management, this study evaluated the effects of mobile health (mHealth) on BP and cholesterol levels in patients after standalone CABG. Methods and results: This study is a post hoc analysis of an observational cohort study among 228 adult pati... Abstract
Cited 2 times since 2023 (1.9 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 31, Issue 5, 29 5 2023, Pages 202-209 Improved prehospital triage for acute cardiac care: results from HART-c, a multicentre prospective study. de Koning ER, Beeres SLMA, Bosch J, Backus BE, Tietge WJ, Alizadeh Dehnavi R, Groenwold RHH, Silvius AM, van Lierop PTS, Jukema JW, Schalij MJ, Boogers MJ
Background: Cardiac symptoms are one of the most prevalent reasons for emergency department visits. However, over 80% of patients with such symptoms are sent home after acute cardiovascular disease has been ruled out. Objective: The Hollands-Midden Acute Regional Triage-cardiology (HART-c) study aimed to investigate whether a novel prehospital triage method, combining prehospital and hospital data with expert consultation, could increase the number of patients who could safely stay at home after... Abstract
Cited 1 times since 2023 (0.8 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 25, Issue 1, 1 1 2023, Pages 49-58 Mobile health vs. standard care after cardiac surgery: results of The Box 2.0 study. Biersteker TE, Boogers MJ, Schalij MJ, Penning de Vries BBL, Groenwold RHH, van Alem AP, de Weger A, van Hof N, Treskes RW
Aims: Postoperative atrial fibrillation (POAF) is a common complication of cardiac surgery, yet difficult to detect in ambulatory patients. The primary aim of this study is to investigate the effect of a mobile health (mHealth) intervention on POAF detection after cardiac surgery. Methods and results: We performed an observational cohort study among 730 adult patients who underwent cardiac surgery at a tertiary care hospital in The Netherlands. Of these patients, 365 patients received standard c... Abstract
Cited 3 times since 2022 (1.8 per year) source: EuropePMC
Prehospital and disaster medicine, Volume 37, Issue 5, 11 2 2022, Pages 600-608 Managing Hospital Capacity: Achievements and Lessons from the COVID-19 Pandemic. de Koning ER, Boogers MJ, Beeres SL, Kramer ID, Dannenberg WJ, Schalij MJ
Introduction: The coronavirus disease 2019 (COVID-19) pandemic challenged health care systems in an unprecedented way. Due to the enormous amount of hospital ward and intensive care unit (ICU) admissions, regular care came to a standstill, thereby overcrowding ICUs and endangering (regular and COVID-19-related) critical care. Acute care coordination centers were set up to safely manage the influx of COVID-19 patients. Furthermore, treatments requiring ICU surveillance were postponed leading to i... Abstract
Cited 8 times since 2021 (2.5 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 29, Issue 4, 18 3 2021, Pages 224-229 Emergency medical services evaluations for chest pain during first COVID-19 lockdown in Hollands-Midden, the Netherlands. de Koning ER, Boogers MJ, Bosch J, de Visser M, Schalij MJ, Beeres SLMA
Objective: To assess whether the COVID-19 lockdown in 2020 had negative indirect health effects, as people seem to have been reluctant to seek medical care. Methods: All emergency medical services (EMS) transports for chest pain or out-of-hospital cardiac arrest (OHCA) in the Dutch region Hollands-Midden (population served > 800,000) were evaluated during the initial 6 weeks of the COVID-19 lockdown and during the same time period in 2019. The primary endpoint was the number of evaluated ches... Abstract
Cited 5 times since 2021 (1.6 per year) source: EuropePMC
BMJ open, Volume 11, Issue 2, 12 2 2021, Pages e041553 Prehospital triage of patients with acute cardiac complaints: study protocol of HART-c, a multicentre prospective study. de Koning E, Biersteker TE, Beeres S, Bosch J, Backus BE, Kirchhof CJ, Alizadeh Dehnavi R, Silvius HA, Schalij M, Boogers MJ
Introduction: Emergency department (ED) overcrowding is a major healthcare problem associated with worse patient outcomes and increased costs. Attempts to reduce ED overcrowding of patients with cardiac complaints have so far focused on in-hospital triage and rapid risk stratification of patients with chest pain at the ED. The Hollands-Midden Acute Regional Triage-Cardiology (HART-c) study aimed to assess the amount of patients left at home in usual ambulance care as compared with the new prehos... Abstract
Cited 2 times since 2020 (0.5 per year) source: EuropePMC
European journal of emergency medicine : official journal of the European Society for Emergency Medicine, Volume 27, Issue 4, 1 1 2020, Pages 243-244 The new era of chest pain evaluation in the Netherlands. Backus BE, Tolsma RT, Boogers MJ
Cited 8 times since 2020 (2 per year) source: EuropePMC
JMIR research protocols, Volume 9, Issue 4, 21 3 2020, Pages e16326 Use of Smart Technology for the Early Diagnosis of Complications After Cardiac Surgery: The Box 2.0 Study Protocol. Biersteker TE, Boogers MJ, de Lind van Wijngaarden RA, Groenwold RH, Trines SA, van Alem AP, Kirchhof CJ, van Hof N, Klautz RJ, Schalij MJ, Treskes RW
Background: Atrial fibrillation (AF), sternal wound infection, and cardiac decompensation are complications that can occur after cardiac surgery. Early detection of these complications is clinically relevant, as early treatment is associated with better clinical outcomes. Remote monitoring with the use of a smartphone (mobile health [mHealth]) might improve the early detection of complications after cardiac surgery. Objective: The primary aim of this study is to compare the detection rate of AF... Abstract
Cited 17 times since 2013 (1.6 per year) source: EuropePMC
PloS one, Volume 8, Issue 7, 10 2 2013, Pages e67936 CT coronary angiography is feasible for the assessment of coronary artery disease in chronic dialysis patients, despite high average calcium scores. de Bie MK, Buiten MS, Gaasbeek A, Boogers MJ, Roos CJ, Schuijf JD, Krol MJ, Rabelink TJ, Bax JJ, Schalij MJ, Jukema JW
Purpose: Significant obstructive coronary artery disease (CAD) is common in asymptomatic dialysis patients. Identifying these high risk patients is warranted and may improve the prognosis of this vulnerable patient group. Routine catheterization of incident dialysis patients has been proposed, but is considered too invasive. CT-angiography may therefore be more appropriate. However, extensive coronary calcification, often present in this patient group, might hamper adequate lumen evaluation. The... Abstract
Cited 3 times since 2013 (0.3 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 40, Issue 8, 29 5 2013, Pages 1171-1180 Automated quantitative coronary computed tomography correlates of myocardial ischaemia on gated myocardial perfusion SPECT. de Graaf MA, El-Naggar HM, Boogers MJ, Veltman CE, Broersen A, Kitslaar PH, Dijkstra J, Kroft LJ, Al Younis I, Reiber JH, Bax JJ, Delgado V, Scholte AJ
Purpose: Automated software tools have permitted more comprehensive, robust and reproducible quantification of coronary stenosis, plaque burden and plaque location of coronary computed tomography angiography (CTA) data. The association between these quantitative CTA (QCT) parameters and the presence of myocardial ischaemia has not been explored. The aim of the present investigation was to evaluate the association between QCT parameters of coronary artery lesions and the presence of myocardial is... Abstract
Cited 7 times since 2012 (0.6 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 14, Issue 3, 19 3 2012, Pages 247-252 Impact of coronary atherosclerosis on the efficacy of radiofrequency catheter ablation for atrial fibrillation. den Uijl DW, Boogers MJ, Compier M, Trines SA, Scholte AJ, Zeppenfeld K, Schalij MJ, Bax JJ, Delgado V
Aims: Coronary atherosclerosis has been associated with the development of atrial fibrillation (AF). However, little is known about the impact of coronary atherosclerosis on the outcome treatment of AF. The aim of this study was to investigate the impact of coronary atherosclerosis on the efficacy of radiofrequency catheter ablation (RFCA) for AF using multi-detector row computed tomography (MDCT). Methods: In 125 consecutive patients undergoing RFCA for AF, a pre-procedural MDCT examination (co... Abstract
Cited 34 times since 2012 (2.9 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 39, Issue 10, 13 2 2012, Pages 1599-1608 Reproducibility of planar (123)I-meta-iodobenzylguanidine (MIBG) myocardial scintigraphy in patients with heart failure. Veltman CE, Boogers MJ, Meinardi JE, Al Younis I, Dibbets-Schneider P, Van der Wall EE, Bax JJ, Scholte AJ
Purpose: Despite its high prognostic value, widespread clinical implementation of (123)I-meta-iodobenzylguanidine (MIBG) myocardial scintigraphy is hampered by a lack of validation and standardization. The purpose of this study was to assess the reliability of planar (123)I-MIBG myocardial scintigraphy in patients with heart failure (HF). Methods: Planar myocardial MIBG images of 70 HF patients were analysed by two experienced and one inexperienced observer. The reproducibility of early and dela... Abstract
Cited 105 times since 2012 (8.6 per year) source: EuropePMC
European heart journal, Volume 33, Issue 8, 26 4 2012, Pages 1007-1016 Automated quantification of coronary plaque with computed tomography: comparison with intravascular ultrasound using a dedicated registration algorithm for fusion-based quantification. Boogers MJ, Broersen A, van Velzen JE, de Graaf FR, El-Naggar HM, Kitslaar PH, Dijkstra J, Delgado V, Boersma E, de Roos A, Schuijf JD, Schalij MJ, Reiber JH, Bax JJ, Jukema JW
Aims: Previous studies have used semi-automated approaches for coronary plaque quantification on multi-detector row computed tomography (CT), while an automated quantitative approach using a dedicated registration algorithm is currently lacking. Accordingly, the study aimed to demonstrate the feasibility and accuracy of automated coronary plaque quantification on cardiac CT using dedicated software with a novel 3D coregistration algorithm of CT and intravascular ultrasound (IVUS) data sets. Meth... Abstract
Cited 16 times since 2011 (1.3 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 38, Issue 11, 18 3 2011, Pages 2031-2039 Left ventricular diastolic dyssynchrony assessed with phase analysis of gated myocardial perfusion SPECT: a comparison with tissue Doppler imaging. Boogers MJ, Chen J, Veltman CE, van Bommel RJ, Mooyaart EA, Al Younis I, van der Hiel B, Dibbets-Schneider P, van der Wall EE, Schalij MJ, Garcia EV, Bax JJ, Delgado V
Purpose: The aim of the current study was to evaluate the feasibility of phase analysis on gated myocardial perfusion SPECT (GMPS) for the assessment of left ventricular (LV) diastolic dyssynchrony in a head-to-head comparison with tissue Doppler imaging (TDI). Methods: The population consisted of patients with end-stage heart failure of New York Heart Association functional class III or IV with a reduced LV ejection fraction of ≤ 35%. LV diastolic dyssynchrony was calculated using TDI as the ma... Abstract
Cited 9 times since 2011 (0.7 per year) source: EuropePMC
The American journal of cardiology, Volume 108, Issue 7, 23 4 2011, Pages 968-972 Prognostic value of renal dysfunction for the prediction of outcome versus results of computed tomographic coronary angiography. Yiu KH, de Graaf FR, Schuijf JD, van Werkhoven JM, van Velzen JE, Boogers MJ, Roos CJ, de Bie MK, Pazhenkottil A, Kroft LJ, Boersma E, Herzog B, de Roos A, Kaufmann PA, Bax JJ, Jukema JW
Chronic kidney disease (CKD) is associated with cardiovascular (CV) events caused by advanced atherosclerosis. Computed tomographic coronary angiography (CTA) can accurately diagnose coronary artery disease (CAD) and predict CV outcomes. The aim of the present study was to evaluate whether moderate CKD provides prognostic information for CV events in patients undergoing CTA. In total 885 patients with suspected CAD underwent CTA and were stratified to moderate CKD (85 patients) or no CKD (770 pa... Abstract
Cited 12 times since 2011 (0.9 per year) source: EuropePMC
Heart failure reviews, Volume 16, Issue 4, 1 1 2011, Pages 411-423 The role of nuclear imaging in the failing heart: myocardial blood flow, sympathetic innervation, and future applications. Boogers MJ, Fukushima K, Bengel FM, Bax JJ
Heart failure represents a common disease affecting approximately 5 million patients in the United States. Several conditions play an important role in the development and progression of heart failure, including abnormalities in myocardial blood flow and sympathetic innervation. Nuclear imaging represents the only imaging modality with sufficient sensitivity to assess myocardial blood flow and sympathetic innervation of the failing heart. Although nuclear imaging with single-photon emission comp... Abstract
Cited 38 times since 2011 (2.9 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 28, Issue 4, 3 1 2011, Pages 921-933 Automatic centerline extraction of coronary arteries in coronary computed tomographic angiography. Yang G, Kitslaar P, Frenay M, Broersen A, Boogers MJ, Bax JJ, Reiber JH, Dijkstra J
Coronary computed tomographic angiography (CCTA) is a non-invasive imaging modality for the visualization of the heart and coronary arteries. To fully exploit the potential of the CCTA datasets and apply it in clinical practice, an automated coronary artery extraction approach is needed. The purpose of this paper is to present and validate a fully automatic centerline extraction algorithm for coronary arteries in CCTA images. The algorithm is based on an improved version of Frangi's vesseln... Abstract
Cited 38 times since 2011 (2.9 per year) source: EuropePMC
The American journal of cardiology, Volume 107, Issue 12, 8 2 2011, Pages 1725-1729 Positive remodeling on coronary computed tomography as a marker for plaque vulnerability on virtual histology intravascular ultrasound. Kröner ES, van Velzen JE, Boogers MJ, Siebelink HM, Schalij MJ, Kroft LJ, de Roos A, van der Wall EE, Jukema JW, Reiber JH, Schuijf JD, Bax JJ
Coronary computed tomographic angiography allows direct evaluation of the vessel wall and thus positive remodeling, which is a marker of vulnerability. The purpose of this study was to assess the association between positive remodeling on computed tomography angiogram (CTA) and vulnerable plaque characteristics on virtual histologic intravascular ultrasound (VH IVUS) images. Forty-five patients (78% men, 58 ± 11 years old) underwent computed tomographic angiography followed by VH IVUS. On CTA, t... Abstract
Cited 20 times since 2011 (1.5 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 4, Issue 3, 1 1 2011, Pages 246-256 Feasibility of diastolic function assessment with cardiac CT: feasibility study in comparison with tissue Doppler imaging. Boogers MJ, van Werkhoven JM, Schuijf JD, Delgado V, El-Naggar HM, Boersma E, Nucifora G, van der Geest RJ, Paelinck BP, Kroft LJ, Reiber JH, de Roos A, Bax JJ, Lamb HJ
Objectives: This study aimed to demonstrate the feasibility of multidetector row computed tomography (CT) for assessment of diastolic function in comparison with 2-dimensional (2D) echocardiography using tissue Doppler imaging (TDI). Background: Diastolic left ventricular (LV) function plays an important role in patients with cardiovascular disease. 2D echocardiography using TDI has been used most commonly to evaluate diastolic LV function. Although the role of cardiac CT imaging for evaluation... Abstract