Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
1716 results
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 25, Issue 3, 1 1 2023, Pages 1194 Analysis of tricuspid regurgitation improvement following cardiac resynchronization therapy-Authors' reply. Stassen J, Bax JJ
Cited 2 times since 2023 (1.9 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 16, Issue 3, 1 1 2023, Pages 332-341 Prognostic Value of Preprocedural LV Global Longitudinal Strain for Post-TAVR-Related Morbidity and Mortality: A Meta-Analysis. Stens NA, van Iersel O, Rooijakkers MJP, van Wely MH, Nijveldt R, Bakker EA, Rodwell L, Pedersen ALD, Poulsen SH, Kjønås D, Stassen J, Bax JJ, Tanner FC, Lerakis S, Shimoni S, Poulin F, Ferreira V, Reskovic Luksic V, van Royen N, Thijssen DHJ
Background: Left ventricular ejection fraction (LVEF) demonstrates limited prognostic value for post-transcatheter aortic valve replacement (TAVR) outcomes. Evidence regarding the potential role of left ventricular global longitudinal strain (LV-GLS) in this setting is inconsistent. Objectives: The aim of this systematic review and meta-analysis of aggregated data was to evaluate the prognostic value of preprocedural LV-GLS for post-TAVR-related morbidity and mortality. Methods: The authors sear... Abstract
Cited 5 times since 2023 (4.6 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 24, Issue 4, 1 1 2023, Pages 542-551 Comparative analysis of right ventricular strain in Fabry cardiomyopathy and sarcomeric hypertrophic cardiomyopathy. Meucci MC, Lillo R, Lombardo A, Lanza GA, Bootsma M, Butcher SC, Massetti M, Manna R, Bax JJ, Crea F, Ajmone Marsan N, Graziani F
Aims: To perform a comparative analysis of right ventricle (RV) myocardial mechanics, assessed by 2D speckle-tracking echocardiography (2D-STE), between patients with Fabry disease and patients with sarcomeric disease. Methods and results: Patients with Fabry cardiomyopathy (FC) (n = 28) were compared with patients with sarcomeric hypertrophic cardiomyopathy (HCM), matched for degree of left ventricle hypertrophy (LVH) and demographic characteristics (n = 112). In addition, patients with Fabry d... Abstract
European heart journal. Cardiovascular Imaging, Volume 24, Issue 4, 1 1 2023, Pages 532-541 Interaction between secondary mitral regurgitation and left atrial function and their prognostic implications after cardiac resynchronization therapy. Stassen J, Galloo X, Hirasawa K, Hirasawa K, van der Bijl P, Leon MB, Marsan NA, Bax JJ
Aims: Left atrial (LA) function is a strong prognostic marker in patients with heart failure and functional mitral regurgitation (MR). Although cardiac resynchronization therapy (CRT) has shown to improve MR severity, the interaction between a reduction in MR severity and an increase in LA function, as well as its association with outcomes, has not been investigated. Methods and results: LA reservoir strain (RS) was evaluated with speckle tracking echocardiography in patients with at least moder... Abstract
Cited 1 times since 2023 (0.9 per year) source: EuropePMC
European heart journal, Volume 44, Issue 10, 1 1 2023, Pages 871-881 Factors influencing post-surgical survival in degenerative mitral regurgitation. Butcher SC, Essayagh B, Steyerberg EW, Benfari G, Antoine C, Grigioni F, Le Tourneau T, Roussel JC, van Wijngaarden A, Marsan NA, Tribouilloy C, Rusinaru D, Hochstadt A, Topilsky Y, Michelena HI, Delgado V, Bax JJ, Enriquez-Sarano M
Aims: Indications for surgery in patients with degenerative mitral regurgitation (DMR) are increasingly liberal in all clinical guidelines but the role of secondary outcome determinants (left atrial volume index ≥60 mL/m2, atrial fibrillation, pulmonary artery systolic pressure ≥50 mmHg and moderate to severe tricuspid regurgitation) and their impact on post-operative outcome remain disputed. Whether these secondary outcome markers are just reflective of the DMR severity or intrinsically affect... Abstract
European heart journal. Cardiovascular Imaging, Volume 24, Issue 4, 1 1 2023, Pages 424-425 The importance of big databases in understanding valvular heart disease. Galloo X, Bax JJ
Heart (British Cardiac Society), Volume 109, Issue 6, 23 4 2023, Pages 478-484 Prognostic impact of left ventricular global longitudinal strain in atrial mitral regurgitation. Meucci MC, Stassen J, Tomsic A, Palmen M, Crea F, Bax JJ, Ajmone Marsan N, Delgado V
Objective: Left atrial (LA) and left ventricular (LV) mechanics are impaired in patients with atrial functional mitral regurgitation (AFMR), but their prognostic value in this subset of patients remains unknown. The present study aimed to evaluate the association between LA and LV longitudinal strain and clinical outcomes in patients with AFMR. Methods: A total of 197 patients (mean age 73±10 years, 44% men) with at least moderate AFMR were retrospectively identified. LV global longitudinal stra... Abstract
JACC. Cardiovascular imaging, Volume 16, Issue 6, 8 2 2023, Pages 837-855 Managing Patients With Moderate Aortic Stenosis. Stassen J, Ewe SH, Pio SM, Pibarot P, Redfors B, Leipsic J, Genereux P, Van Mieghem NM, Kuneman JH, Makkar R, Hahn RT, Playford D, Marsan NA, Delgado V, Ben-Yehuda O, Leon MB, Bax JJ
Current guidelines recommend that clinical surveillance for patients with moderate aortic stenosis (AS) and aortic valve replacement (AVR) may be considered if there is an indication for coronary revascularization. Recent observational studies, however, have shown that moderate AS is associated with an increased risk of cardiovascular events and mortality. Whether the increased risk of adverse events is caused by associated comorbidities, or to the underlying moderate AS itself, is incompletely... Abstract
Cited 4 times since 2023 (3.5 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 16, Issue 2, 3 1 2023, Pages e014672 Pericoronary Adipose Tissue Attenuation in Patients With Acute Coronary Syndrome Versus Stable Coronary Artery Disease. Kuneman JH, van Rosendael SE, van der Bijl P, van Rosendael AR, Kitslaar PH, Reiber JHC, Jukema JW, Leon MB, Ajmone Marsan N, Knuuti J, Bax JJ
Background: Pericoronary adipose tissue (PCAT) attenuation has been associated with coronary inflammation and can be evaluated with coronary computed tomography angiography. The aims of this study were to compare the PCAT attenuation across precursors of culprit and nonculprit lesions of patients with acute coronary syndrome versus stable coronary artery disease (CAD). Methods: In this case-control study, patients with suspected CAD who underwent coronary computed tomography angiography were inc... Abstract
Cited 1 times since 2023 (0.9 per year) source: EuropePMC
Diabetes care, Volume 46, Issue 2, 1 1 2023, Pages 416-424 Diabetes, Atherosclerosis, and Stenosis by AI. Jonas RA, Crabtree TR, Jennings RS, Marques H, Katz RJ, Chang HJ, Stuijfzand WJ, van Rosendael AR, Choi JH, Doh JH, Her AY, Koo BK, Nam CW, Park HB, Shin SH, Cole J, Gimelli A, Khan MA, Lu B, Gao Y, Nabi F, Nakazato R, Schoepf UJ, Driessen RS, Bom MJ, Thompson RC, Jang JJ, Ridner M, Rowan C, Avelar E, Généreux P, Knaapen P, de Waard GA, Pontone G, Andreini D, Al-Mallah MH, Guglielmo M, Bax JJ, Earls JP, Min JK, Choi AD, Villines TC
Objective: This study evaluates the relationship between atherosclerotic plaque characteristics (APCs) and angiographic stenosis severity in patients with and without diabetes. Whether APCs differ based on lesion severity and diabetes status is unknown. Research design and methods: We retrospectively evaluated 303 subjects from the Computed TomogRaphic Evaluation of Atherosclerotic Determinants of Myocardial IsChEmia (CREDENCE) trial referred for invasive coronary angiography with coronary compu... Abstract
European heart journal. Cardiovascular Imaging, Volume 24, Issue 3, 1 1 2023, Pages 327-335 Feature-tracking computed tomography left atrial strain and long-term survival after transcatheter aortic valve implantation. Hirasawa K, Singh GK, Kuneman JH, Gegenava T, van der Kley F, Hautemann D, Reiber JHC, Ajmone Marsan N, Bax JJ, Delgado V
Aims: Aortic stenosis (AS) induces left atrial (LA) remodelling through the increase of left ventricular (LV) filling pressures. Peak LA longitudinal strain (PALS), reflecting LA reservoir function, has been proposed as a prognostic marker in patients with AS. Feature-tracking (FT) multi-detector computed tomography (MDCT) allows assessment of LA strain from MDCT data. The aim of this study is to investigate the association between PALS using FT MDCT and survival in patients with severe AS who u... Abstract
Cited 5 times since 2023 (4.3 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 81, Issue 8, 1 1 2023, Pages 743-752 Cardiac Damage and Quality of Life After Aortic Valve Replacement in the PARTNER Trials. Généreux P, Cohen DJ, Pibarot P, Redfors B, Bax JJ, Zhao Y, Prince H, Makkar RR, Kapadia S, Thourani VH, Mack MJ, Nazif TM, Lindman BR, Babaliaros V, Russo M, McCabe JM, Gillam LD, Alu MC, Hahn RT, Webb JG, Leon MB, Arnold SV
Background: The extent of extravalvular cardiac damage is associated with increased risk of adverse events among patients with severe aortic stenosis undergoing aortic valve replacement (AVR). Objectives: The goal was to describe the association of cardiac damage on health status before and after AVR. Methods: Patients from the PARTNER (Placement of Aortic Transcatheter Valves) 2 and 3 trials were pooled and classified by echocardiographic cardiac damage stage at baseline and 1 year as previousl... Abstract
Cited 2 times since 2023 (1.7 per year) source: EuropePMC
Rheumatology (Oxford, England), Volume 62, Issue SI, 1 1 2023, Pages SI20-SI31 Evaluation of left cardiac chamber function with cardiac magnetic resonance and association with outcome in patients with systemic sclerosis. Butcher SC, Vos JL, Fortuni F, Galloo X, Liem SIE, Bax JJ, Delgado V, Vonk MC, van Leuven SI, Snoeren M, El Messaoudi S, de Vries-Bouwstra JK, Nijveldt R, Ajmone Marsan N
Objective: This study aimed to determine whether lower values of feature-tracking cardiovascular magnetic resonance (CMR)-derived left atrial reservoir strain (LARS) and impaired left ventricular (LV) global longitudinal strain (GLS) were associated with the presence of symptoms and long-term prognosis in patients with SSc. Methods: A total of 100 patients {54 [interquartile range (IQR) 46-64] years, 42% male} with SSc who underwent CMR imaging at two tertiary referral centres were included. All... Abstract
Cited 1 times since 2023 (0.9 per year) source: EuropePMC
Circulation. Arrhythmia and electrophysiology, Volume 16, Issue 2, 25 4 2023, Pages e011676 Prognostic Implications of Right Ventricular Size and Function in Patients Undergoing Cardiac Resynchronization Therapy. Galloo X, Stassen J, Hirasawa K, Mertens BJA, Cosyns B, van der Bijl P, Delgado V, Ajmone Marsan N, Bax JJ
Cited 1 times since 2023 (0.8 per year) source: EuropePMC
Clinical cardiology, Volume 46, Issue 3, 24 4 2023, Pages 320-327 Risk factors based vessel-specific prediction for stages of coronary artery disease using Bayesian quantile regression machine learning method: Results from the PARADIGM registry. Park HB, Lee J, Hong Y, Byungchang S, Kim W, Lee BK, Lin FY, Hadamitzky M, Kim YJ, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, Gonçalves PA, Leipsic JA, Shin S, Choi JH, Virmani R, Samady H, Chinnaiyan K, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Kook W, Chang HJ
Background and hypothesis: The recently introduced Bayesian quantile regression (BQR) machine-learning method enables comprehensive analyzing the relationship among complex clinical variables. We analyzed the relationship between multiple cardiovascular (CV) risk factors and different stages of coronary artery disease (CAD) using the BQR model in a vessel-specific manner. Methods: From the data of 1,463 patients obtained from the PARADIGM (NCT02803411) registry, we analyzed the lumen diameter st... Abstract
Journal of the American College of Cardiology, Volume 81, Issue 3, 1 1 2023, Pages e25 Reply: Outcomes in Bicuspid Aortic Valve Disease. Hecht S, Bax JJ, Pibarot P
Cited 10 times since 2023 (8.1 per year) source: EuropePMC
European heart journal, Volume 44, Issue 1, 1 1 2023, Pages 28-40 Valvular heart disease: shifting the focus to the myocardium. Ajmone Marsan N, Delgado V, Shah DJ, Pellikka P, Bax JJ, Treibel T, Cavalcante JL
Adverse cardiac remodelling is the main determinant of patient prognosis in degenerative valvular heart disease (VHD). However, to give an indication for valvular intervention, current guidelines include parameters of cardiac chamber dilatation or function which are subject to variability, do not directly reflect myocardial structural changes, and, more importantly, seem to be not sensitive enough in depicting early signs of myocardial dysfunction before irreversible myocardial damage has occurr... Abstract
European heart journal, Volume 44, Issue 2, 1 1 2023, Pages 159-161 Guideline-based use of cardiac imaging for chronic coronary syndromes. van der Bijl P, Stassen J, Bax JJ
Cited 2 times since 2022 (1.6 per year) source: EuropePMC
JACC. Cardiovascular interventions, Volume 16, Issue 2, 28 4 2022, Pages 140-151 Staging Heart Failure Patients With Secondary Mitral Regurgitation Undergoing Transcatheter Edge-to-Edge Repair. Stolz L, Doldi PM, Orban M, Karam N, Puscas T, Wild MG, Popescu A, von Bardeleben RS, Iliadis C, Baldus S, Adamo M, Thiele H, Besler C, Unterhuber M, Ruf T, Pfister R, Higuchi S, Koell B, Giannini C, Petronio A, Kassar M, Weckbach LT, Butter C, Stocker TJ, Neuss M, Melica B, Braun D, Windecker S, Massberg S, Praz F, Näbauer M, Kalbacher D, Lurz P, Metra M, Bax JJ, Hausleiter J, EuroSMR Investigators
Background: Secondary mitral regurgitation (SMR) is a progressive disease with characteristic pathophysiological changes that may influence prognosis. Although the staging of SMR patients suffering from heart failure with reduced ejection fraction (HFrEF) according to extramitral cardiac involvement has prognostic value in medically treated patients, such data are so far lacking for edge-to-edge mitral valve repair (M-TEER). Objectives: This study sought to classify M-TEER patients into disease... Abstract
Circulation, Volume 147, Issue 10, 27 4 2022, Pages 798-811 The MIDA-Q Mortality Risk Score: A Quantitative Prognostic Tool for the Mitral Valve Prolapse Spectrum. Essayagh B, Benfari G, Antoine C, Grigioni F, Le Tourneau T, Roussel JC, Bax JJ, Delgado V, Ajmone Marsan N, van Wijngaarden A, Tribouilloy C, Rusinaru D, Hochstadt A, Topilsky Y, Thapa P, Michelena HI, Enriquez-Sarano M
Background: Mitral valve prolapse (MVP) is responsible for a considerable disease burden but is widely heterogeneous. The lack of a comprehensive prognostic instrument covering the entire MVP spectrum, encompassing the quantified consequent degenerative mitral regurgitation (DMR), hinders clinical management and therapeutic trials. Methods: The new Mitral Regurgitation International Database Quantitative (MIDA-Q) registry enrolled 8187 consecutive patients (ages 63±16 years, 47% women, follow-up... Abstract